Gene Symbol | FOXC1 |
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Entrez Gene | 2296 |
Alt Symbol | ARA, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3 |
Species | Human |
Gene Type | protein-coding |
Description | forkhead box C1 |
Other Description | forkhead box C1 protein|forkhead box protein C1|forkhead, drosophila, homolog-like 7|forkhead-related activator 3|forkhead-related protein FKHL7|forkhead-related transcription factor 3|forkhead/winged helix-like transcription factor 7|myeloid factor-delta |
Swissprots | Q9UP06 Q86UP7 Q9UDD0 Q12948 Q9NUE5 Q9BYM1 |
Accessions | AAC18081 AAC72915 AAP15181 ACS83750 AHI85954 EAW55074 Q12948 AK021858 BC134421 AAI34422 BC169306 AAI69306 BC169307 AAI69307 L12143 AAK13575 U13221 AAA92038 NM_001453 NP_001444 |
Function | Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5'- GTAAACAAA-3' in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye. {ECO:0000269|PubMed:17993506}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in all tissues and cell lines examined. {ECO:0000269|PubMed:8499623}. |
Human FOXC1 peptide - ab26345 from Abcam
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Human FOXC1 peptide - ab23069 from Abcam
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Human FOXC1 protein fragment - ab152388 from Abcam
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FOXC1 Antibody Blocking Peptide - LS-E25561 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E13241 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E11293 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E26001 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E9846 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E13641 from LifeSpan Bioscience
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FOXC1 Antibody Blocking Peptide - LS-E13640 from LifeSpan Bioscience
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FoxC1 Partial Protein - H00002296-Q01 from Novus Biologicals
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FOXC1-Antibody-C-term-Blocking-Peptide - BP8907b from Abgent, a WuXi AppTec company
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FOXC1 (C Term) blocking peptide - GTX25079-PEP from GeneTex
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FOXC1 (internal) blocking peptide - GTX89469-PEP from GeneTex
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FOXC1/2 Peptide - orb224368 from Biorbyt
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Goat anti FOXC1 antibody Immunizing peptide - orb17287 from Biorbyt
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FOXC1 Immunizing peptide - orb17517 from Biorbyt
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FOXC1 Peptide - AC21-0390-P from Abcore
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FOXC1 Peptide - AC21-0829-P from Abcore
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FOXC1 / FKHL7 / FREAC3 - H00002296-Q01 from Acris Antibodies
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FOXC1 / FKHL7 / FREAC3 - H00002296-Q01-25 from Acris Antibodies
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FOXC1 Peptide - 45-603P from ProSci
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FOXC1 Peptide - 45-604P from ProSci
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Recombinant Forkhead Box Protein C1 (FOXC1) - RPA763Mu01 from Uscn Life Science Inc.
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FOXC1/2 Blocking Peptide - CBP3482 from Cohesion Biosciences
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