Gene Symbol | FOXC1 |
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Entrez Gene | 2296 |
Alt Symbol | ARA, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3 |
Species | Human |
Gene Type | protein-coding |
Description | forkhead box C1 |
Other Description | forkhead box C1 protein|forkhead box protein C1|forkhead, drosophila, homolog-like 7|forkhead-related activator 3|forkhead-related protein FKHL7|forkhead-related transcription factor 3|forkhead/winged helix-like transcription factor 7|myeloid factor-delta |
Swissprots | Q9UP06 Q86UP7 Q9UDD0 Q12948 Q9NUE5 Q9BYM1 |
Accessions | AAC18081 AAC72915 AAP15181 ACS83750 AHI85954 EAW55074 Q12948 AK021858 BC134421 AAI34422 BC169306 AAI69306 BC169307 AAI69307 L12143 AAK13575 U13221 AAA92038 NM_001453 NP_001444 |
Function | Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Regulates FOXO1 through binding to a conserved element, 5'- GTAAACAAA-3' in its promoter region, implicating FOXC1 as an important regulator of cell viability and resistance to oxidative stress in the eye. {ECO:0000269|PubMed:17993506}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in all tissues and cell lines examined. {ECO:0000269|PubMed:8499623}. |
FoxC1 Antibody - 7415 from Cell Signaling Technology
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FoxC1 (D8A6) Rabbit mAb - 8758 from Cell Signaling Technology
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FOXC1 (C-18) - sc-21396 from Santa Cruz Biotechnology
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FOXC1 (N-19) - sc-21394 from Santa Cruz Biotechnology
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Anti-FOXC1 antibody - ab117088 from Abcam
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Anti-FOXC1 antibody - ab24067 from Abcam
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Anti-FOXC1 antibody - ab94650 from Abcam
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Anti-FOXC1 antibody - ab115201 from Abcam
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Anti-FOXC1 antibody - ab136078 from Abcam
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Anti-FOXC1 antibody - ab97742 from Abcam
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Anti-FOXC1 antibody - ChIP Grade - ab5079 from Abcam
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Anti-FOXC1 Antibody (aa460-474) - LS-C6939 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa178-190) - LS-C54852 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (clone 4D11) - LS-C197229 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, AP) - LS-C219384 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, APC) - LS-C219382 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa406-455) - LS-C31270 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, Biotin) - LS-C219385 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, FITC) - LS-C219386 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, Azide-free, HRP) - LS-C219387 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (C-Terminus, PE) - LS-C219388 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa275-325) - LS-C290191 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa375-425) - LS-C290193 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa62-186, Biotin) - LS-C300277 from LifeSpan Bioscience
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Anti-FOXC1 Antibody (aa62-186, FITC) - LS-C301991 from LifeSpan Bioscience
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