TNFRSF10C

Gene Symbol TNFRSF10C
Entrez Gene 8794
Alt Symbol CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Other Description TNF-related apoptosis-inducing ligand receptor 3|antagonist decoy receptor for TRAIL/Apo-2L|cytotoxic TRAIL receptor-3|decoy TRAIL receptor without death domain|decoy receptor 1|lymphocyte inhibitor of TRAIL|tumor necrosis factor receptor superfamily member 10C
Swissprots Q08AS6 O14755 O14798 Q6UXM5 Q6FH98
Accessions AAM82564 CAT16333 CBA12840 EAW63638 O14798 AF012536 AAB67104 AF012629 AAB67110 AF014794 AAC05593 AF016267 AAB81181 AF020502 AAB71413 AF033854 AAB87506 AK298664 BAG60832 AK298718 BAH12853 AK313213 BAG36028 AY358281 AAQ88648 BC017852 AAH17852 BC125041 AAI25042 BC125042 AAI25043 BG545631 CR541857 CAG46655 DC380668 NM_003841 NP_003832
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Top Pathways Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

DcR1 CRISPR/Cas9 KO Plasmid (h) - sc-406305 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 HDR Plasmid (h) - sc-406305-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 Double Nickase Plasmid (h) - sc-406305-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 Double Nickase Plasmid (h2) - sc-406305-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 CRISPR Activation Plasmid (h) - sc-406305-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 CRISPR Activation Plasmid (h2) - sc-406305-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 Lentiviral Activation Particles (h) - sc-406305-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 Lentiviral Activation Particles (h2) - sc-406305-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DcR1 siRNA (h) - sc-40235 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DcR1 shRNA Plasmid (h) - sc-40235-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DcR1 shRNA (h) Lentiviral Particles - sc-40235-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAIL R3/TNFRSF10C RNAi - H00008794-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU097041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21740 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21740 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03315 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03315

TNFRSF10C siRNA (Human) - CRH5794 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF10C - MBS827675 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF10C shRNA Plasmid (Human) - CHH5794 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFRSF10C miRNA 3'UTR clone - MiUTR3H-06119 from Creative biogene

Species Reactivities Human
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