TNFRSF10C

Gene Symbol	TNFRSF10C
Entrez Gene	8794
Alt Symbol	CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Other Description	TNF-related apoptosis-inducing ligand receptor 3|antagonist decoy receptor for TRAIL/Apo-2L|cytotoxic TRAIL receptor-3|decoy TRAIL receptor without death domain|decoy receptor 1|lymphocyte inhibitor of TRAIL|tumor necrosis factor receptor superfamily member 10C
Swissprots	Q08AS6 O14755 O14798 Q6UXM5 Q6FH98
Accessions	AAM82564 CAT16333 CBA12840 EAW63638 O14798 AF012536 AAB67104 AF012629 AAB67110 AF014794 AAC05593 AF016267 AAB81181 AF020502 AAB71413 AF033854 AAB87506 AK298664 BAG60832 AK298718 BAH12853 AK313213 BAG36028 AY358281 AAQ88648 BC017852 AAH17852 BC125041 AAI25042 BC125042 AAI25043 BG545631 CR541857 CAG46655 DC380668 NM_003841 NP_003832
Function	Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity	Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Top Pathways	Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human DcR1 full length protein - ab157352 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source HEK 293 cells Species Human

DcR1 peptide - ab5849 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

DcR1 peptide - ab6096 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

DcR1 peptide - ab7880 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human DcR1 full length protein - ab160192 from Abcam Category Protein Source Wheat germ Species Human

Human DcR1 protein fragment - ab151632 from Abcam Category Protein Source HEK 293 cells Species Human

TRAIL-R3 / DCR1 Antibody Blocking Peptide - LS-E10655 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRAIL-R3 / DCR1 Antibody Blocking Peptide - LS-E29908 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TRAIL-R3 / DCR1 Antibody Blocking Peptide - LS-E29939 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TRAIL R3/TNFRSF10C Recombinant Protein - H00008794-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

TRAIL R3/TNFRSF10C Blocking Peptide - NBP1-76881PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TRAIL R3/TNFRSF10C Blocking Peptide - NBP1-77295PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

DcR1 peptide - GTX27880 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Recombinant Human TRAIL R3/TNFRSF10C Fc Chimera - 630-TR-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human TRAIL R3/TNFRSF10C Fc Chimera, CF - 630-TR-100/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human TNFRSF10C (Fc) protein - orb180437 from Biorbyt Category Protein Prices $213.00, $408.00, $850.00, $1,088.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

Human TRAILR3 protein - orb49696 from Biorbyt Category Protein Prices $196.00, $349.00, $995.00, $1,386.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

TNFRSF10C Blocking Peptide - 33R-5730 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TNFRSF10C protein (His tag) - 80R-4187 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CD263 / TRAILR3 (26-236, His-tag) - AR51875PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD263 / TRAILR3 (26-236, His-tag) - AR51875PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CD263 / TRAILR3 - H00008794-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

CD263 / TRAILR3 Control Peptide - AP30279CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CD263 / TRAILR3 control peptide - SP5362CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Tumor Necrosis Factor Receptor Superfamily Member 10C, TNFRSF10C, Human, Recombinant - 19-C504 from ARP American Research Products Category Protein Prices $109.00 Sizes 10 µg Source HEK293 Species Human

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