TNFRSF10C

Gene Symbol TNFRSF10C
Entrez Gene 8794
Alt Symbol CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Other Description TNF-related apoptosis-inducing ligand receptor 3|antagonist decoy receptor for TRAIL/Apo-2L|cytotoxic TRAIL receptor-3|decoy TRAIL receptor without death domain|decoy receptor 1|lymphocyte inhibitor of TRAIL|tumor necrosis factor receptor superfamily member 10C
Swissprots Q08AS6 O14755 O14798 Q6UXM5 Q6FH98
Accessions AAM82564 CAT16333 CBA12840 EAW63638 O14798 AF012536 AAB67104 AF012629 AAB67110 AF014794 AAC05593 AF016267 AAB81181 AF020502 AAB71413 AF033854 AAB87506 AK298664 BAG60832 AK298718 BAH12853 AK313213 BAG36028 AY358281 AAQ88648 BC017852 AAH17852 BC125041 AAI25042 BC125042 AAI25043 BG545631 CR541857 CAG46655 DC380668 NM_003841 NP_003832
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Top Pathways Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

DcR1 Antibody - 4756 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Jurkat, Raji and A20 cell lines, using DcR1 Antibody.

DcR1 (C-6) - sc-365279 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DcR1 (C-6): sc-365279. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

DcR1 (H-129) - sc-28984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DcR1 (H-129): sc-28984. Western blot analysis of DcR1 expression in human PBL whole cell lysate.

DcR1 (N-19) - sc-7193 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DcR1 (N-19): sc-7193. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing membrane and cytoplasmic staining of glandular cells.

DcR1 (S-12) - sc-26462 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DcR1 (S-12): sc-26462. Western blot analysis of DcR1 expression in Jurkat (A) and Raji (B) whole cell lysates.

DcR1/2 (H-16) - sc-26461 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DcR1 antibody - ab2087 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DcR1 antibody (ab2087) at 1 µg/mlLane 1 : Hela cell lysateLane 2 : Mouse liver tissue lysateLane 3 : Rat liver tissue lysate

Anti-DcR1 antibody - ab1674 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab1674 recognizes a 66kDa band of expected size in Lane 1 containing TRAIL-3R-Fc protein and showed minimal or no crossreactivity to TRAIL-2R-Fc protein in Lane 2.

Anti-DcR1 antibody - ab52926 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal

Anti-DcR1 antibody - ab5808 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DcR1 antibody - ab180777 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DcR1 antibody (ab180777) at 1/500 dilution + Human spleen cell lysate

Anti-DcR1 antibody [B-D44] - ab46849 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-D44

Anti-DcR1 antibody [B-D44] - ab46850 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-D44

Anti-DcR1 antibody [B-D44] (Phycoerythrin) - ab46861 from Abcam

Prices $216.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-D44

Anti-DcR1 antibody [B-H47] - ab59507 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-H47

Anti-DcR1 antibody [EPR6162] - ab133658 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6162
All lanes : Anti-DcR1 antibody [EPR6162] (ab133658) at 1/1000 dilutionLane 1 : Human spleen lysateLane 2 : JAR cell lysateLane 3 : Human tonsil lysateLane 4 : Jurkat cell lysateLane 5 : A549 cell lysateLane 6 : Human fetal heart lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-DcR1 antibody [EPR6162] (Alexa Fluor® 647) - ab199543 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6162
ab199543 staining DcR1 in Jurkat cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab199543 at 1/50 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-DcR1 antibody [EPR6162] (HRP) - ab199544 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6162
All lanes : Anti-DcR1 antibody [EPR6162] (HRP) (ab199544) at 1/5000 dilutionLane 1 : Tonsil (Human) Whole Cell Lysate - adult normal tissueLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLane 4 : Heart (Human) Tissue Lysate - fetal normal tissueLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under non-reducing conditions.

Anti-TRAIL-R3 / DCR1 Antibody - LS-C14812 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R3 / DCR1 Antibody (aa149-157) - LS-C14813 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R3 / DCR1 Antibody - LS-C14814 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TRAIL-R3 / DCR1 Antibody - LS-C14816 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TRAIL-R3 / DCR1 Antibody (N-Terminus) - LS-C18134 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TRAIL-R3 / DCR1 Antibody - LS-C18649 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-TRAIL-R3 / DCR1 Antibody (C-Terminus) - LS-C36142 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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