CACYBP

Gene Symbol	CACYBP
Entrez Gene	27101
Alt Symbol	GIG5, PNAS-107, S100A6BP, SIP
Species	Human
Gene Type	protein-coding
Description	calcyclin binding protein
Other Description	S100A6-binding protein|Siah-interacting protein (SIP)|calcyclin-binding protein|growth-inhibiting gene 5 protein|hCacyBP
Swissprots	B3KSF1 Q5R370 Q9HB71 Q5R371 O60666 B2ZWH2
Accessions	CAC22475 EAW90982 EAW90983 Q9HB71 AF057356 AAC21458 AF275803 AAG23817 AF314752 AAG34170 AK093425 BAG52713 AK294042 BAG57394 AK313278 BAG36086 AL035305 CAA22910 AW300675 AY423723 AAS00486 BC005975 AAH05975 BC022352 AAH22352 BC067823 AAH67823 BC078151 AAH78151 BQ432793 CA951015 NM_001007214 NP_001007215 NM_014412 NP_055227
Function	May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). {ECO:0000269|PubMed:16085652}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12895292}. Cytoplasm {ECO:0000269|PubMed:12895292}. Note=Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CacyBP CRISPR/Cas9 KO Plasmid (h) - sc-418064 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP HDR Plasmid (h) - sc-418064-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP Double Nickase Plasmid (h) - sc-418064-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP Double Nickase Plasmid (h2) - sc-418064-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP CRISPR Activation Plasmid (h) - sc-418064-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP CRISPR Activation Plasmid (h2) - sc-418064-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP Lentiviral Activation Particles (h) - sc-418064-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP Lentiviral Activation Particles (h2) - sc-418064-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CacyBP siRNA (h) - sc-88504 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CacyBP shRNA Plasmid (h) - sc-88504-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CacyBP shRNA (h) Lentiviral Particles - sc-88504-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CACYBP RNAi - H00027101-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CACYBP RNAi - H00027101-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU110331 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5281 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5281 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10727 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10727

CACYBP siRNA (Human) - CRH8964 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CACYBP - MBS827873 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CACYBP(NM_001007214.1) - SHG132739 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CACYBP(NM_014412.2) - SHG132757 from Creative biogene Category siRNA Species Reactivities Human

CACYBP shRNA Plasmid (Human) - CHH8964 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CACYBP miRNA 3'UTR clone - MiUTR1H-01618 from Creative biogene Species Reactivities Human

CACYBP miRNA 3'UTR clone - MiUTR1H-01619 from Creative biogene Species Reactivities Human

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