ALOXE3

Gene Symbol ALOXE3
Entrez Gene 59344
Alt Symbol ARCI3, E-LOX, eLOX-3, eLOX3
Species Human
Gene Type protein-coding
Description arachidonate lipoxygenase 3
Other Description e-LOX-3|epidermal LOX-3|epidermal lipoxygenase|epidermis-type lipoxygenase 3|hydroperoxide isomerase ALOXE3|hydroperoxy icosatetraenoate dehydratase
Swissprots Q9HC22 Q3ZB74 B2R981 B7Z3W0 Q9BYJ1 Q9H4F2
Accessions CAC34518 EAW90093 EAW90094 Q9BYJ1 AF182218 AAG16899 AJ269499 CAC12843 AK292732 BAF85421 AK296416 BAH12346 AK299742 BAH13114 AK313677 BAG36428 BC101938 AAI01939 BC101939 AAI01940 BC103508 AAI03509 BC104724 AAI04725 DA183156 DC376381 NM_001165960 NP_001159432 NM_021628 NP_067641
Function Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty acid hydroperoxides. In the skin, acts downstream of ALOX12B on the linoleate moiety of esterified omega-hydroxyacyl- sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. In parallel, it may have a signaling f
Subcellular Location Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00726}.
Tissue Specificity Predominantly expressed in skin.

ALOXE3 (H-85) - sc-367483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ALOXE3 (N-14) - sc-133273 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

ALOXE3 (T-14) - sc-133275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 antibody - ab118470 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ALOXE3 antibody (ab118470) at 1/500 dilution + Human fetal lung lysate

Anti-ALOXE3 antibody - ab95935 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ALOXE3 antibody (ab95935) at 1/1000 dilution + HepG2 cell lysate at 30 µg

Anti-ALOXE3 antibody - ab73091 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ALOXE3 antibody (ab73091) at 1/500 dilutionLane 1 : ALOXE3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-ALOXE3 Antibody (aa223-252, AP) - LS-C232559 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa223-252, Biotin) - LS-C232561 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa223-252, APC) - LS-C232562 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa223-252) - LS-C156292 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ALOXE3 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The ALOXE3 antibody detected the ALOXE3 protein (arrow).

Anti-ALOXE3 Antibody (aa223-252, FITC) - LS-C232563 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa334-599) - LS-C178646 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa223-252, PE) - LS-C232564 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa334-599) - LS-C179034 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa223-252, Azide-free, HRP) - LS-C249403 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody - LS-C306213 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa230-260) - LS-C319438 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 Antibody (aa1-294) - LS-C185876 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded NCI-N87 xenograft using ALOXE3 antibody at 1:500 dilution.

ALOXE3 Antibody - NBP1-91661 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALOXE3 Antibody [NBP1-91661] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue

ALOXE3 Antibody - NBP1-32533 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALOXE3 Antibody [NBP1-32533] - Sample(30 ug whole cell lysate)A:Hep G2 7. 5% SDS PAGE, antibody diluted at 1:1000.

ALOXE3 Antibody - H00059344-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ALOXE3 Antibody [H00059344-B01P] - Analysis of ALOXE3 expression in transfected 293T cell line by ALOXE3 polyclonal antibody. Lane 1: ALOXE3 transfected lysate(78.21 KDa). Lane 2: Non-transfected lysate.

ALOXE3 Polyclonal Antibody - bs-7856R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ALOXE3 antibody produced in mouse - SAB1407831 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ALOXE3: <B>Cat. No. SAB1407831</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~78.2 kDa using ALOXE3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ALOXE3 (32-45) antibody produced in rabbit - SAB1104364 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human ALOXE3 was separated on SDS-PAGE, blotted with Anti-ALOXE3 (32-45) (<B>Cat. No. SAB1104364</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-ALOXE3 antibody produced in rabbit - HPA023120 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ALOXE3: <B>Cat. No. HPA023120</B>: Immunohistochemical staining of human stomach, upper shows strong cytoplasmic and nuclear positivity in glandular cells.
Search more