ALOXE3

Gene Symbol	ALOXE3
Entrez Gene	59344
Alt Symbol	ARCI3, E-LOX, eLOX-3, eLOX3
Species	Human
Gene Type	protein-coding
Description	arachidonate lipoxygenase 3
Other Description	e-LOX-3|epidermal LOX-3|epidermal lipoxygenase|epidermis-type lipoxygenase 3|hydroperoxide isomerase ALOXE3|hydroperoxy icosatetraenoate dehydratase
Swissprots	Q9HC22 Q3ZB74 B2R981 B7Z3W0 Q9BYJ1 Q9H4F2
Accessions	CAC34518 EAW90093 EAW90094 Q9BYJ1 AF182218 AAG16899 AJ269499 CAC12843 AK292732 BAF85421 AK296416 BAH12346 AK299742 BAH13114 AK313677 BAG36428 BC101938 AAI01939 BC101939 AAI01940 BC103508 AAI03509 BC104724 AAI04725 DA183156 DC376381 NM_001165960 NP_001159432 NM_021628 NP_067641
Function	Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty acid hydroperoxides. In the skin, acts downstream of ALOX12B on the linoleate moiety of esterified omega-hydroxyacyl- sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. In parallel, it may have a signaling f
Subcellular Location	Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00726}.
Tissue Specificity	Predominantly expressed in skin.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ALOXE3 ELISA Kit (Sandwich ELISA) - LS-F7304 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.114 ng/ml Range 0.313-20 ng/ml

Human ALOXE3 ELISA Kit - abx150621 from Abbexa Category ELISA Kit Sensitivity 0.114 ng/ml Range 0.313 ng/ml - 20 ng/ml

Arachidonate Lipoxygenase 3, ALOXE3, Human, ELISA Kit - E-EL-H0413 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Arachidonate Lipoxygenase 3 (ALOXE3), Human, ELISA Kit - SED085Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.114ng/mL Range 0.312-20ng/mL

ALOXE3 (Arachidonate Lipoxygenase 3), Rabbit, ELISA Kit - E-EL-RB1663 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ALOXE3 (Arachidonate Lipoxygenase 3), Chicken, ELISA Kit - E-EL-Ch2010 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ALOXE3 (Arachidonate Lipoxygenase 3), Pig, ELISA Kit - E-EL-P1502 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ALOXE3 (Arachidonate Lipoxygenase 3), Sheep, ELISA Kit - E-EL-S0335 from ARP American Research Products Category ELISA Kit Prices $988.00 Sizes 96 t

ALOXE3 (Arachidonate Lipoxygenase 3), Monkey, ELISA Kit - E-EL-MK1327 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

Human ALOXE3(Arachidonate Lipoxygenase 3) ELISA Kit - E-EL-H0413 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Human ALOXE3 (Arachidonate Lipoxygenase 3) CLIA Kit - E-CL-H0333 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

ALOXE3, ELISA Kit - MBS2510989 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313--20ng/mL

arachidonate lipoxygenase 3, ELISA Kit - MBS9338620 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Arachidonate Lipoxygenase 3 (ALOXE3), ELISA Kit - MBS2020039 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.114ng/mL. Range 0.313-20ng/mL

ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) - SED085Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) - SED085Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Arachidonate Lipoxygenase 3 (ALOXE3) ELISA Kit - EKU02553 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.114 ng/mL Range 0.312-20 ng/mL

Human ALOXE3(Arachidonate Lipoxygenase 3) ELISA Kit - E-EL-H0413 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mLng/mL Range 0.31~20 ng/mL

Human DPYD (Dihydropyrimidine Dehydrogenase) CLIA Kit - E-CL-H0299 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human Arachidonate Lipoxygenase 3 ELISA Kit - abx251996 from Abbexa Category ELISA Kit Sensitivity 0.188 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human ALOXE3 ELISA Kit (Sandwich ELISA) - LS-F21934 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.188 ng/ml Range 0.313-20 ng/ml

Arachidonate Lipoxygenase 3 (ALOXE3), Human, ELISA Kit - DL-ALOXE3-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

ALOXE3 (Arachidonate Lipoxygenase 3), CLIA Kit - MBS2533005 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

Human ALOXE3 ELISA Kit - abx572541 from Abbexa Category ELISA Kit Sensitivity 0.114 ng/ml Range 0.313 ng/ml - 20 ng/ml

ALOXE3 - EKH5234 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.313--20ng/ml

Search more