AKR1C2

Gene Symbol	AKR1C2
Entrez Gene	1646
Alt Symbol	AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member C2
Other Description	3-alpha-HSD3|aldo-keto reductase family 1 member C2|chlordecone reductase homolog HAKRD|dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III|pseudo-chlordecone reductase|testicular 17,20-desmolase deficiency|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type II dihydrodiol dehydrogenase
Swissprots	Q96A71 Q14133 Q7M4N1 B4DKR9 A8K2N9 P52895 Q5SR16
Accessions	AAB38486 ABD36086 BAA92891 CAD88527 P52895 AB021654 BAA36169 AB031084 BAA92884 AB209017 BAD92254 AK091194 AK290304 BAF82993 AK296419 BAG59081 AK296686 BAG59281 AK308385 BC007024 AAH07024 BC063574 AAH63574 BT006653 AAP35299 CA450425 DA451165 DA458030 DQ890680 ABM81606 DQ893862 ABM84788 M33376 S68330 AAD14013 U05598 AAA20937 XM_011519342 XP_011517644 NM_001135241 NP_001128713 NM_001354 NP_001345 NM_205845 NP_995317
Function	Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. {ECO:0000269|PubMed:15929998, ECO:0000269|PubMed:17034817, ECO:0000269|PubMed:17442338, ECO:0000269|PubMed:8573067}.
Subcellular Location	Cytoplasm {ECO:0000305}.
Tissue Specificity	Expressed in fetal testes. Expressed in fetal and adult adrenal glands. {ECO:0000269|PubMed:21802064}.
Top Pathways	Steroid hormone biosynthesis, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BABP / AKR1C2 ELISA Kit (Sandwich ELISA) - LS-F8182 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.156-10 ng/ml

Aldo-keto reductase family 1 member C2 (AKR1C2), Human, ELISA Kit - E01A1372 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000pg/ml

Aldo-keto reductase family 1 member C2, AKR1C2, Human, ELISA Kit - E2111h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Dihydrodiol Dehydrogenase 2 (DDH2), Human, ELISA Kit - SEQ200Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

AKR1C2 (Human) Matched Antibody Pair - H00001646-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Androstenedione, ELISA Kit - MBS037472 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS026480 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS063095 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS041610 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS023947 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS024205 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1nmol/L. Range 0.625nmol/L-20nmol/L.

Androstenedione, ELISA Kit - MBS035994 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS092059 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS078764 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS035011 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS047300 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS009947 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS041435 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 nmol/L. Range 0.625 nmol/L - 20 nmol/L.

Androstenedione, ELISA Kit - MBS032749 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS019958 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS096509 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione, ELISA Kit - MBS102142 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione (ASD), ELISA Kit - MBS260899 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.05ng/ml. Range 10 ng/ml-0.156 ng/ml

Androstenedione (ASD), ELISA Kit - MBS269409 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Androstenedione (ASD), ELISA Kit - MBS266358 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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