AADAT

Gene Symbol AADAT
Entrez Gene 51166
Alt Symbol KAT2, KATII
Species Human
Gene Type protein-coding
Description aminoadipate aminotransferase
Other Description 2-aminoadipate aminotransferase|2-aminoadipate transaminase|KAT/AadAT|L kynurenine/alpha aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II|kynurenine--oxoglutarate aminotransferase II|kynurenine--oxoglutarate transaminase 2|kynurenine--oxoglutarate transaminase II|kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Swissprots Q9UL02 B3KP84 Q8N5Z0
Accessions AAY41030 EAX04770 EAX04771 EAX04772 Q8N5Z0 AF481738 AAM09683 AI190763 AK055952 BAG51596 AK314729 BAG37271 BC031068 AAH31068 HQ447955 ADQ32439 XM_006714231 XP_006714294 XM_011532020 XP_011530322 NM_001286682 NP_001273611 NM_001286683 NP_001273612 NM_016228 NP_057312 NM_182662 NP_872603
Function Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). {ECO:0000269|PubMed:18620547}.
Subcellular Location Mitochondrion {ECO:0000305}.
Tissue Specificity Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
Top Pathways Lysine degradation, Tryptophan metabolism, Lysine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism

KAT II (B-4) - sc-365847 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KAT II (B-4): sc-365847. Western blot analysis of KAT II expression in EOC 20 whole cell lysate.

KAT II (D-13) - sc-54018 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KAT II (G-4) - sc-377158 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KAT II (G-4): sc-377158. Western blot analysis of KAT II expression in EOC 20 (A), IMR-32 (B), H4 (C), SK-N-SH (D) and BC3H1 (E) whole cell lysates.

KAT II (H-301) - sc-67377 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KAT II (H-301): sc-67377. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

KAT II (M-300) - sc-67376 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KAT II (M-300): sc-67376. Western blot analysis of KAT II expression in HeLa whole cell lysate.

KAT II (S-19) - sc-54021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KAT II (S-19): sc-54021. Western blot analysis of KAT II expression in non-transfected: sc-117752 (A) and mouse KAT II transfected: sc-121178 (B) 293T whole cell lysates.

KAT II (P-17) - sc-54020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Aminoadipate aminotransferase antibody - ab59132 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Aminoadipate aminotransferase antibody (ab59132) at 1.25 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Aminoadipate aminotransferase antibody - ab89608 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Aminoadipate aminotransferase antibody (ab89608) at 1 µg/ml + Human liver lysate at 50 µgdeveloped using the ECL technique

Anti-Aminoadipate aminotransferase antibody - ab77395 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Aminoadipate aminotransferase antibody (ab77395) at 1 µg/ml + Human Liver lysate (in RIPA buffer) at 35 µg

Anti-Aminoadipate aminotransferase antibody - ab140693 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue (after heat induced antigen retrieval) labelling Aminoadipate aminotransferase with ab140693 at 5 µg/ml.

Anti-KATII / AADAT Antibody - LS-C137469 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa51-100) - LS-C31995 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
AADAT antibody LS-C31995 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-KATII / AADAT Antibody (aa215-264) - LS-C110798 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AADAT antibody LS-C110798 Western blot of COLO205 cell lysate.

Anti-KATII / AADAT Antibody (N-Terminus) - LS-C209343 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (Internal) - LS-C209367 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa196-224, APC) - LS-C232283 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa196-224, Biotin) - LS-C232284 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa196-224, AP) - LS-C232285 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa183-196) - LS-C112639 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AADAT antibody (1 ug/ml) staining of Human Liver lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-KATII / AADAT Antibody (aa196-224, FITC) - LS-C232286 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody (aa196-224, PE) - LS-C232287 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody - LS-C306008 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-KATII / AADAT Antibody - LS-C309272 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KATII / AADAT Antibody - LS-C309277 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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