AADAT

Gene Symbol	AADAT
Entrez Gene	51166
Alt Symbol	KAT2, KATII
Species	Human
Gene Type	protein-coding
Description	aminoadipate aminotransferase
Other Description	2-aminoadipate aminotransferase|2-aminoadipate transaminase|KAT/AadAT|L kynurenine/alpha aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II|kynurenine--oxoglutarate aminotransferase II|kynurenine--oxoglutarate transaminase 2|kynurenine--oxoglutarate transaminase II|kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Swissprots	Q9UL02 B3KP84 Q8N5Z0
Accessions	AAY41030 EAX04770 EAX04771 EAX04772 Q8N5Z0 AF481738 AAM09683 AI190763 AK055952 BAG51596 AK314729 BAG37271 BC031068 AAH31068 HQ447955 ADQ32439 XM_006714231 XP_006714294 XM_011532020 XP_011530322 NM_001286682 NP_001273611 NM_001286683 NP_001273612 NM_016228 NP_057312 NM_182662 NP_872603
Function	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). {ECO:0000269|PubMed:18620547}.
Subcellular Location	Mitochondrion {ECO:0000305}.
Tissue Specificity	Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
Top Pathways	Lysine degradation, Tryptophan metabolism, Lysine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Aminoadipate aminotransferase full length protein - ab162437 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Aminoadipate aminotransferase protein fragment - ab162438 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

KATII / AADAT Antibody Blocking Peptide - LS-E81 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KATII / AADAT Antibody Blocking Peptide - LS-E16017 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KATII / AADAT Antibody Blocking Peptide - LS-E26571 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KATII / AADAT Antibody Blocking Peptide - LS-E29667 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KATII / AADAT Antibody Blocking Peptide - LS-E29668 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KATII / AADAT Antibody Blocking Peptide - LS-E29669 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human alpha-Aminoadipate Aminotransferase Protein - H00051166-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human alpha-Aminoadipate Aminotransferase Protein - H00051166-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AADAT-Antibody-Center-Blocking-peptide - BP10161c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Aminoadipate aminotransferase blocking peptide - GTX88607-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human alpha-Aminoadipate Aminotransferase, CF - 7927-AT-010 from R&D Systems Category Protein Source E. coli-derived, Met1-Leu425, with an N-terminal Gly-Arg-Ala-His

AADAT Blocking Peptide - 33R-2491 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AADAT Blocking Peptide - 33R-1601 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Aminoadipate Aminotransferase Peptide - AC21-1407-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

AADAT - H00051166-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AADAT - H00051166-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AADAT - H00051166-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AADAT - H00051166-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AADAT Peptide - 42-742P from ProSci Category Peptide Species Human

AADAT fusion protein - ag3676 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Aminoadipate Aminotransferase (AADAT) - RPD856Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Kynurenine Aminotransferase II - pro10416 from Covalab Category Protein Source Escherichia coli Species Human

Recombinant Aminoadipate Aminotransferase (AADAT) - RPD856Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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