AADAT

Gene Symbol	AADAT
Entrez Gene	51166
Alt Symbol	KAT2, KATII
Species	Human
Gene Type	protein-coding
Description	aminoadipate aminotransferase
Other Description	2-aminoadipate aminotransferase|2-aminoadipate transaminase|KAT/AadAT|L kynurenine/alpha aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II|kynurenine--oxoglutarate aminotransferase II|kynurenine--oxoglutarate transaminase 2|kynurenine--oxoglutarate transaminase II|kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Swissprots	Q9UL02 B3KP84 Q8N5Z0
Accessions	AAY41030 EAX04770 EAX04771 EAX04772 Q8N5Z0 AF481738 AAM09683 AI190763 AK055952 BAG51596 AK314729 BAG37271 BC031068 AAH31068 HQ447955 ADQ32439 XM_006714231 XP_006714294 XM_011532020 XP_011530322 NM_001286682 NP_001273611 NM_001286683 NP_001273612 NM_016228 NP_057312 NM_182662 NP_872603
Function	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). {ECO:0000269|PubMed:18620547}.
Subcellular Location	Mitochondrion {ECO:0000305}.
Tissue Specificity	Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
Top Pathways	Lysine degradation, Tryptophan metabolism, Lysine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-AADAT-cDNA-Clone - DC06203 from Abgent, a WuXi AppTec company Prices $579.15 Sizes 10 µg Species Human Accession BC031068

AADAT - MBS1270390 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC031068

Human Aminoadipate aminotransferase Gene ORF cDNA clone in cloning vector - HG16667-U from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG16667-ACR from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG16667-ANR from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG16667-ANG from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG16667-ACG from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, C-Flag tag - HG16667-CF from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, C-His tag - HG16667-CH from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, C-Myc tag - HG16667-CM from Sino Biological Species Human

Human AADAT Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG16667-CY from Sino Biological Species Human Accession NM_016228.3

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-Flag tag - HG16667-NF from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-His tag - HG16667-NH from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-Myc tag - HG16667-NM from Sino Biological Species Human

Human Aminoadipate aminotransferase Gene ORF cDNA clone expression plasmid, N-HA tag - HG16667-NY from Sino Biological Species Human

Human AADAT natural ORF mammalian expression plasmid - HG16667-UT from Sino Biological Species Human Accession NM_016228.3

Human AADAT ORF Clone(NM_016228.3) - CDCR300789 from Creative biogene Species Human

Human AADAT ORF Clone(NM_182662.1) - CDCR324145 from Creative biogene Species Human

Human AADAT ORF Clone (BC031068) - CDCS414222 from Creative biogene Species Human Accession Q4W5N8

Human AADAT cDNA Clone(NM_016228.3) - CDFG000072 from Creative biogene Species Human

Human AADAT cDNA Clone(NM_182662.1) - CDFG012136 from Creative biogene Species Human

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