CPSF2

Gene Symbol CPSF2
Entrez Gene 53981
Alt Symbol CPSF100
Species Human
Gene Type protein-coding
Description cleavage and polyadenylation specific factor 2, 100kDa
Other Description CPSF 100 kDa subunit|CPSF 100kDa subunit|cleavage and polyadenylation specificity factor 100 kDa subunit|cleavage and polyadenylation specificity factor subunit 2
Swissprots B3KME1 Q9H3W7 Q6NSJ1 Q9P2I0
Accessions EAW81480 EAW81481 EAW81482 EAW81483 Q9P2I0 AB037788 BAA92605 AK001627 BAG50953 AK001912 BAG50992 AK023583 BAG51207 AL442079 CAC09445 AU132572 BC060854 BC070095 AAH70095 BU071571 DB081880 XM_005267767 XP_005267824 NM_017437 NP_059133
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. {ECO:0000269|PubMed:14749727, ECO:0000269|PubMed:18688255}.
Subcellular Location Nucleus {ECO:0000305}.
Top Pathways mRNA surveillance pathway

CPSF2 (A-6) - sc-398539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPSF2 (A-6): sc-398539. Western blot analysis of CPSF2 expression in HeLa (A), Ramos (B), HL-60 (C) and BJAB (D) nuclear extracts.

CPSF2 (A-9) - sc-398589 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPSF2 (A-9): sc-398589. Western blot analysis of CPSF2 expression in HeLa (A), Ramos (B), HL-60 (C), Jurkat (D) and BJAB (E) nuclear extracts.

CPSF2 (A-11) - sc-165983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPSF2 (A-11): sc-165983. Western blot analysis of CPSF2 expression in BJAB (A), Ramos (B), HeLa (C), HL-60 (D) and Jurkat (E) nuclear extracts.

CPSF2 (P-20) - sc-26658 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPSF2 (P-20): sc-26658. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

CPSF2 (C-18) - sc-26659 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPSF2 (C-18): sc-26659. Western blot analysis of CPSF2 expression in BJAB (A), Ramos (B), HL-60 (C), Jurkat (D) and NIH/3T3 (E) nuclear extracts.

Anti-CPSF2 antibody - ab81553 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pancreatic islet cell tumor (left) and mouse teratoma (right) tissues labelling CPSF2 with ab81553 at 1/200 (1µg/ml). Detection: DAB.

Anti-CPSF2 antibody - ab81554 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CPSF2 antibody (ab81554) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-CPSF2 antibody - ab100807 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab100807, at 1/250 dilution, staining CPSF2 in Human ovarian carcinoma by immunohistochemistry.

Anti-CPSF2 antibody - ab69356 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CPSF2 antibody (ab69356) at 1/500 dilution + human placenta tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-CPSF2 antibody [EPR7599] - ab126760 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7599
All lanes : Anti-CPSF2 antibody [EPR7599] (ab126760) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Ramos cell lysateLane 3 : Jurkat cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit at 1/2000 dilution

Anti-CPSF2 Antibody (aa450-500) - LS-C288373 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse CPSF100 by Immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-CPSF100 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-CPSF2 Antibody (clone 2200C3a) - LS-C342754 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2200C3a
Western blot analysis of immunized recombinant protein, using anti-CPSF2 monoclonal antibody.

Anti-CPSF2 Antibody (aa450-500) - LS-C286764 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Mouse CPSF100 Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-CPSF100 used at a dilution of 1:250.

Anti-CPSF2 Antibody - LS-C125372 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPSF2 Antibody (clone 2200C3a) - LS-C184723 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2200C3a

Anti-CPSF2 Antibody (aa550-600) - LS-C288372 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CPSF2 Antibody (aa732-782) - LS-C288374 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CPSF2 Antibody - LS-C307073 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CPSF2 Antibody (Internal, clone EPR7599) - LS-C152386 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR7599
Western blot analysis on (A) HeLa, (B) Ramos, (C) Jurkat, and (D) 293T cell lysates using anti-CPSF2 antibody.

Anti-CPSF2 Antibody (aa73-122) - LS-C80379 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

CPSF2 Antibody - NB100-79823 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CPSF2 Antibody [NB100-79823] - Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. CPSF100 was also immunoprecipitated by rabbit anti-CPSF100 antibodies NB100-79824 and NB100-79825.

CPSF2 Antibody - NBP1-82910 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CPSF2 Antibody [NBP1-82910] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

CPSF2 Antibody - H00053981-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CPSF2 Antibody [H00053981-B01P] - Analysis of CPSF2 expression in human placenta.

CPSF2 Antibody - NBP2-15988 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CPSF2 Antibody [NBP2-15988] - Sample (50 ug of whole cell lysate) A: Mouse Liver, 7. 5% SDS PAGE gel, diluted at 1:500.

CPSF2 Antibody - H00053981-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CPSF2 Antibody [H00053981-A01] - CPSF2 polyclonal antibody (A01), Lot # 061101JCS1 Western Blot analysis of CPSF2 expression in SJCRH30 ( Cat # L027V1 ).
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