CPSF2

Gene Symbol CPSF2
Entrez Gene 53981
Alt Symbol CPSF100
Species Human
Gene Type protein-coding
Description cleavage and polyadenylation specific factor 2, 100kDa
Other Description CPSF 100 kDa subunit|CPSF 100kDa subunit|cleavage and polyadenylation specificity factor 100 kDa subunit|cleavage and polyadenylation specificity factor subunit 2
Swissprots B3KME1 Q9H3W7 Q6NSJ1 Q9P2I0
Accessions EAW81480 EAW81481 EAW81482 EAW81483 Q9P2I0 AB037788 BAA92605 AK001627 BAG50953 AK001912 BAG50992 AK023583 BAG51207 AL442079 CAC09445 AU132572 BC060854 BC070095 AAH70095 BU071571 DB081880 XM_005267767 XP_005267824 NM_017437 NP_059133
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. {ECO:0000269|PubMed:14749727, ECO:0000269|PubMed:18688255}.
Subcellular Location Nucleus {ECO:0000305}.
Top Pathways mRNA surveillance pathway

Human CPSF2 Gene cDNA clone plasmid - HG11512-M from Sino Biological

Species Human

Human CPSF2 ORF clone (NM_017437.1) - CDCB160356 from Creative biogene

Species Human
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