CLEC2A

Gene Symbol	CLEC2A
Entrez Gene	387836
Alt Symbol	INPE5792, KACL, PILAR, UNQ5792
Species	Human
Gene Type	protein-coding
Description	C-type lectin domain family 2, member A
Other Description	C-type lectin domain family 2 member A|keratinocyte-associated C-type lectin|proliferation-induced lymphocyte-associated receptor
Swissprots	A9QKS2 Q6UVW9 A9QKS3 A5Y4G5
Accessions	EAW96129 EAW96130 Q6UVW9 AY359126 AAQ89483 EF127467 ABO33172 EU095393 ABW79912 EU095394 ABW79913 XM_011520654 XP_011518956 XM_011520655 XP_011518957 XM_011520656 XP_011518958 XM_011520657 XP_011518959 XR_931289 NM_001130711 NP_001124183 NM_207375 NP_997258
Function	Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti- apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity. {ECO:0000269|PubMed:18550855, ECO:0000269|PubMed:20194751}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855}; Single-pass type II membrane protein {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855}.
Tissue Specificity	Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferating lymphocytes. Not detected in myeloid leukocytes or natural killer (NK) cells. {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855, ECO:0000269|PubMed:20194751}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLEC2A peptide - ab103565 from Abcam Category Peptide

CLEC2A Antibody Blocking Peptide - LS-E709 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLEC2A Antibody Blocking Peptide - LS-E31308 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CLEC2A Antibody Blocking Peptide - LS-E24301 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLEC2A-Antibody-Center-Blocking-peptide - BP11060c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human CLEC-2A, CF - 8435-CL-050 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived, Trp49-Leu174 (Gly136Asp), with an N-terminal HA tag

CLEC2A (N-term) Control Peptide - AP55437CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CLEC2A Peptide - 6959P from ProSci Category Peptide Species Human

Recombinant Human C-type lectin domain family 2 member A(CLEC2A) - CSB-YP744258HU CSB-EP744258HU CSB-BP744258HU CSB-MP744258HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human CLEC-2A Protein, CF - 8435-CL from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Human embryonic kidney cell, HEK293-derived Trp49-Leu174 (Gly136Asp), with an N-terminal HA tag Species Human

CLEC2A Peptide - abx164605 from Abbexa Category Peptide Species Human

CLEC2A - TP325182 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

C-type lectin domain family 2 member A (CLEC2A), Recombinant Protein - MBS1461315 from MyBioSource Category Protein Prices $865.00, $865.00, $1,085.00, $1,085.00, $1,255.00, $1,255.00, $1,710.00, $1,710.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CLEC-2A Recombinant Protein Antigen - NBP2-14641PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CLEC2A Peptide, Human - M34GP03261H from Creative Peptides Category Peptide Source Synthetic. Species Human

CLEC-2A Recombinant Protein Antigen - NBP2-56052PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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