CLEC2A

Gene Symbol	CLEC2A
Entrez Gene	387836
Alt Symbol	INPE5792, KACL, PILAR, UNQ5792
Species	Human
Gene Type	protein-coding
Description	C-type lectin domain family 2, member A
Other Description	C-type lectin domain family 2 member A|keratinocyte-associated C-type lectin|proliferation-induced lymphocyte-associated receptor
Swissprots	A9QKS2 Q6UVW9 A9QKS3 A5Y4G5
Accessions	EAW96129 EAW96130 Q6UVW9 AY359126 AAQ89483 EF127467 ABO33172 EU095393 ABW79912 EU095394 ABW79913 XM_011520654 XP_011518956 XM_011520655 XP_011518957 XM_011520656 XP_011518958 XM_011520657 XP_011518959 XR_931289 NM_001130711 NP_001124183 NM_207375 NP_997258
Function	Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti- apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity. {ECO:0000269|PubMed:18550855, ECO:0000269|PubMed:20194751}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855}; Single-pass type II membrane protein {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855}.
Tissue Specificity	Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferating lymphocytes. Not detected in myeloid leukocytes or natural killer (NK) cells. {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855, ECO:0000269|PubMed:20194751}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CLEC-2A (K-14) - sc-167485 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

CLEC-2A (N-13) - sc-167486 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-CLEC2A antibody - ab76711 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLEC2A antibody [MM0698-15R10] - ab201608 from Abcam Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone MM0698-15R10

Anti-CLEC2A Antibody (aa79-107, APC) - LS-C233925 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107, Biotin) - LS-C233926 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107, AP) - LS-C233927 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107, FITC) - LS-C233929 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107, Azide-free, HRP) - LS-C249691 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107) - LS-C320434 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107, PE) - LS-C233930 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (aa79-107) - LS-C168833 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (C-Terminus) - LS-C169862 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CLEC2A Antibody (N-Terminus) - LS-C153625 from LifeSpan Bioscience Prices $345.00, $1,035.00 Sizes 100 µg, 500 µg Host Rabbit Clonality Polyclonal

CLEC-2A Antibody (705529) - MAB72191 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 705529

CLEC-2A Antibody (705518) - MAB7219 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 705518

CLEC-2A Antibody - NBP2-14641 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CLEC2A antibody produced in rabbit - SAB3500809 from Sigma-Aldrich Prices $341.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

ANTI-CLEC2A (CENTER) antibody produced in rabbit - SAB1301908 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CLEC2A antibody produced in rabbit - HPA048530 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CLEC2A Antibody - C-terminal region (ARP67046_P050) - ARP67046_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

CLEC2A Antibody - middle region (OAAB01079) - OAAB01079 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

CLEC2A-Antibody-Center - AP11060c from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Human CLEC-2A Antibody - MAB7219 from R&D Systems Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clone 705518

Human CLEC-2A MAb (Clone 705518), Mouse IgG1 - MAB7219-SP from R&D Systems Host Mouse Clonality Monoclonal Clone 705518

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