TNIP2

Gene Symbol TNIP2
Entrez Gene 79155
Alt Symbol ABIN2, FLIP1, KLIP
Species Human
Gene Type protein-coding
Description TNFAIP3 interacting protein 2
Other Description A20-binding inhibitor of NF-kappaB activation-2|TNFAIP3-interacting protein 2|fetal liver LKB1-interacting protein
Swissprots D3DVQ9 Q9H682 Q7L5L2 B3KTY8 Q8NFZ5 Q9BQR6 B1AKS4
Accessions CAM28233 EAW82514 EAW82515 EAW82516 Q8NFZ5 AF372839 AAM21315 AJ304866 CAC34835 AK026176 BAB15382 AK096296 BAG53250 AL137262 BC002740 AAH02740 BX386180 CB157550 DA421921 NM_001161527 NP_001154999 NM_001292016 NP_001278945 NM_024309 NP_077285
Function Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes. {ECO:0000269|PubMed:12595760, ECO:0000269|PubMed:12753905, ECO:0000269|PubMed:12933576, ECO:0000269|PubMed:14653779, ECO:0000269|PubMed:15169888, ECO:0000269|PubMed:21784860}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12595760}. Nucleus {ECO:0000305}.
Tissue Specificity Ubiquitously expressed in all tissues examined. {ECO:0000269|PubMed:12595760}.

Abin-2 (H-8) - sc-271850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Abin-2 (H-8): sc-271850. Western blot analysis of Abin-2 expression in SW480 whole cell lysate.

Abin-2 (N-16) - sc-32637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Abin-2 (K-17) - sc-32638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Abin-2 (K-17): sc-32638. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing nuclear staining of glandular cells.

Abin-2 (H-300) - sc-50526 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Abin-2 (H-300): sc-50526. Western blot analysis of Abin-2 expression in SW480 (A), HL-60 (B), Hep G2 (C) and NCI-H226 (D) whole cell lysates and mouse heart tissue extract (E).

Anti-TNIP2 antibody - ab155513 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TNIP2 antibody (ab155513) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : HeLaS3 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-TNIP2 antibody - ab129801 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TNIP2 antibody (ab129801) at 1/100 dilution + HL60 cell lysate at 35 µg

Anti-TNIP2 antibody - ab13683 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody - LS-C11710 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody - LS-C11712 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody - LS-C63397 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, AP) - LS-C241965 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, APC) - LS-C241967 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, Biotin) - LS-C241968 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, FITC) - LS-C241969 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, PE) - LS-C241970 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194, Azide-free, HRP) - LS-C247100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa66-115) - LS-C151865 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TNIP2 / ABIN-2 antibody Western Blot of NCI-H226 cell lysate.

Anti-TNIP2 / ABIN-2 Antibody (aa127-374, Biotin) - LS-C301054 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa127-374, FITC) - LS-C303229 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa164-194) - LS-C330239 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TNIP2 / ABIN-2 Antibody (aa165-194) - LS-C160082 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TNIP2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The TNIP2 antibody detected the TNIP2 protein (arrow).

Anti-TNIP2 / ABIN-2 Antibody (aa127-374) - LS-C296854 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TNIP2 / ABIN-2.

Anti-TNIP2 / ABIN-2 Antibody IHC-plus™ - LS-B2082 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TNIP2 antibody IHC of human brain cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2082 concentration 5 ug/ml.

TNIP2 Antibody - NB100-56701 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

TNIP2 Antibody - NBP1-32689 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TNIP2 Antibody [NBP1-32689] - Sample (30 ug of whole cell lysate)A: A431 B: Hela S310% SDS PAGE, antibody diluted at 1:1000.
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