LECT1

Gene Symbol LECT1
Entrez Gene 11061
Alt Symbol BRICD3, CHM-I, CHM1, MYETS1
Species Human
Gene Type protein-coding
Description leukocyte cell derived chemotaxin 1
Other Description BRICHOS domain containing 3|chondromodulin I|chondromodulin-1|chondromodulin-I|leukocyte cell-derived chemotaxin 1|multiple myeloma tumor suppressor 1
Swissprots Q5TAM4 Q9UM18 O75829 Q8TAY6
Accessions AAC98971 BAA77384 EAW52047 EAW52048 O75829 AB005999 BAA86262 AB006000 BAA33443 AY368652 AAQ72693 BC025659 AAH25659 CR541910 CAG46708 XM_006719761 XP_006719824 XM_011534897 XP_011533199 XM_011534898 XP_011533200 XM_011534899 XP_011533201 XM_011534900 XP_011533202 NM_001011705 NP_001011705 NM_007015 NP_008946
Function Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. {ECO:0000269|PubMed:16980969}.
Subcellular Location Chondromodulin-1: Secreted, extracellular space, extracellular matrix. Note=Accumulated in the inter- territorial matrix of cartilage.
Tissue Specificity Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma. {ECO:0000269|PubMed:16980969}.

ChM-1 (H-10) - sc-365693 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ChM-1 (H-10): sc-365693. Western blot analysis of ChM-1 expression in non-transfected: sc-117752 (A) and human ChM-1 transfected: sc-114096 (B) 293T whole cell lysates.

ChM-1 (H-300) - sc-33563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ChM-1 (H-300): sc-33563. Western blot analysis of ChM-1 expression in human PBL whole cell lysate.

ChM-1 (K-20) - sc-34275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ChM-1 (K-20): sc-34275. Western blot analysis of human recombinant ChM-1 fusion protein.

ChM-1 (P-17) - sc-34276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ChM-1 (P-17): sc-34276. Western blot analysis of human recombinant ChM-1 fusion protein.

ChM-1 (C-20) - sc-20310 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ChM-1 (C-20): sc-20310. Western blot analysis of human recombinant ChM-1 fusion protein.

Anti-LECT1 antibody - ab80511 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LECT1 antibody (ab80511) at 1 µg/ml + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LECT1 antibody - ab68542 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-LECT1 antibody (ab68542) at 1/500 dilutionLane 1 : LECT1 293T transfected cell lysateLane 2 : non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L) at 1/5000 dilution

Anti-LECT1 antibody - Carboxyterminal end - ab71450 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LECT1 antibody - Carboxyterminal end (ab71450) at 1/60 dilution + NCI-H460 cell line lysates at 12.5 µgObserved band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-LECT1 / Chondromodulin-I Antibody - LS-C311336 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LECT1 / Chondromodulin-I Antibody - LS-C311339 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LECT1 / Chondromodulin-I Antibody - LS-C335695 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of A549 cell using LECT1 antibody. Blue: DAPI for nuclear staining.

Anti-LECT1 / Chondromodulin-I Antibody (aa110-159) - LS-C80668 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.

Anti-LECT1 / Chondromodulin-I Antibody (aa134-334) - LS-C314919 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LECT1 / Chondromodulin-I.

Anti-LECT1 / Chondromodulin-I Antibody (aa253-281) - LS-C98597 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Chondromodulin-1/LECT1 Antibody (394002) - MAB41681 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 394002

Chondromodulin-1/LECT1 Antibody - NBP1-59348 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Chondromodulin-1/LECT1 Antibody - NBP1-84484 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Chondromodulin-1/LECT1 Antibody [NBP1-84484] - Staining of human liver shows moderate granular cytoplasmic positivity in hepatocytes.

Chondromodulin-1/LECT1 Antibody - H00011061-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-B01] - analysis of LECT1 expression in transfected 293T cell line by LECT1 MaxPab polyclonal antibody (B01). Lane 1: LECT1 transfected lysate (37.10 KDa). Lane 2: Non-transfected lysate.

Chondromodulin-1/LECT1 Antibody - H00011061-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-D01P] - Analysis of LECT1 expression in transfected 293T cell line by LECT1 polyclonal antibody.Lane 1: LECT1 transfected lysate(37.10 KDa).Lane 2: Non-transfected lysate.

Chondromodulin-1/LECT1 Antibody - H00011061-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-B01P] - Analysis of LECT1 expression in transfected 293T cell line by LECT1 polyclonal antibody. Lane 1: LECT1 transfected lysate(36.74 KDa). Lane 2: Non-transfected lysate.

Anti-LECT1 antibody produced in rabbit - HPA010510 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LECT1: <B>Cat. No. HPA010510</B>: Immunohistochemical staining of human liver shows moderate granular cytoplasmic positivity in hepatocytes.

Anti-LECT1 antibody produced in rabbit - SAB2101331 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LECT1: <B>Cat. No.SAB2101331</B>: LECT1 in 721_B cell lysate with LECT1 antibody at 1.0 μg/mL.

Anti-LECT1 (C-term) antibody produced in rabbit - SAB1300680 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LECT1 (C-term) Antibody: <B>Cat. No. SAB1300680</B>: LECT1 in human testis tissue with Anti-LECT1 (C-term) Antibody at 40 μg/mL.

Anti-LECT1 antibody produced in rabbit - SAB1401557 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-LECT1, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401557</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~37.10 kDa using LECT1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-LECT1 (N-term) antibody produced in rabbit - SAB1300679 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LECT1 (N-term) Antibody: <B>Cat. No. SAB1300679</B>: LECT1 in human lung carcinoma tissue with Anti-LECT1 (N-term) Antibody at 40 μg/mL.
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