AGBL5

Gene Symbol AGBL5
Entrez Gene 60509
Alt Symbol CCP5
Species Human
Gene Type protein-coding
Description ATP/GTP binding protein-like 5
Other Description ATP/GTP-binding protein-like 5|cytosolic carboxypeptidase 5|cytosolic carboxypeptidase-like protein 5
Swissprots Q96IK8 Q53SZ0 B7Z7I7 Q9H6V0 Q9H8P8 Q8NDL9 A2VDI7 B7WPG9 D6W548 Q53SW0
Accessions AAX93164 AAY14655 EAX00649 EAX00650 EAX00651 EAX00652 EAX00653 Q8NDL9 AI990522 AK023398 BAB14560 AK025492 BAB15151 AK302091 BAH13623 AL833844 CAD38704 BC007415 AAH07415 BC018562 BC018584 BC062326 BC131498 AAI31499 CB155754 DA901318 XM_005264477 XP_005264534 XM_006712058 XP_006712121 XM_011533011 XP_011531313 XM_011533012 XP_011531314 XM_011533013 XP_011531315 NM_001035507 NP_001030584 NM_021831 NP_068603 NR_104246
Function Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post- translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. {ECO:0000250|UniProtKB:Q09M02}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09M02}. Nucleus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23085998}. Midbody {ECO:0000269|PubMed:23085998}. Note=Mainly cytoplasmic. Slight accumulation in the nucleus is observed (By similarity). Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis. {ECO:0000250|UniProtKB:Q09M02, ECO:0000269|PubMed:23085998}.
Tissue Specificity Expressed in brain.

CCP5 (G-19) - sc-246230 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CCP5 (G-19): sc-246230. Western blot analysis of CCP5 expression in U-251-MG whole cell lysate.

CCP5 (N-18) - sc-246228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CCP5 (N-18): sc-246228. Western blot analysis of CCP5 expression in mouse skin tissue extract.

CCP5 (T-20) - sc-246229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CCP5 (T-20): sc-246229. Western blot analysis of CCP5 expression in non-transfected: sc-117752 (A) and human CCP5 transfected: sc-369147 (B) 293T whole cell lysates.

CCP5 (W-25) - sc-133445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 antibody - ab118621 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AGBL5 antibody (ab118621) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : 786 O cell lysateLane 3 : Human fetal brain lysate

Anti-AGBL5 antibody - ab72265 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-AGBL5 antibody (ab72265) at 1/500 dilutionLane 1 : AGBL5 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-AGBL5 antibody - N-terminal - ab170541 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of U 251MG cells labeling AGBL5 with ab170541 at 1/10 (green). DAPI was used to stain the cell nuclear (blue).

Anti-AGBL5 Antibody (aa106-135, AP) - LS-C232491 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa106-135, APC) - LS-C232492 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa106-135, Biotin) - LS-C232493 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa601-650) - LS-C81801 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-AGBL5 Antibody (aa588-637) - LS-C82767 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-AGBL5 Antibody (aa106-135, FITC) - LS-C232494 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa106-135, PE) - LS-C232496 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa106-135, Azide-free, HRP) - LS-C249390 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody - LS-C306129 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AGBL5 Antibody (aa137-149) - LS-C154862 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AGBL5 antibody (1 ug/ml) staining of Mouse Skin lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-AGBL5 Antibody - LS-C309350 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa106-135) - LS-C319370 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGBL5 Antibody (aa99-127) - LS-C156146 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AGBL5 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

AGBL5 Antibody - NBP2-30016 from Novus Biologicals

Prices $299.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

AGBL5 Antibody - NBP1-83616 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: AGBL5 Antibody [NBP1-83616] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

AGBL5 Antibody - NBP1-56622 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AGBL5 Antibody [NBP1-56622] - 721_B cell lysate, concentration 0.2-1 ug/ml.

AGBL5 Antibody - H00060509-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

AGBL5 Antibody - H00060509-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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