Gene Symbol | CCL15 |
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Entrez Gene | 6359 |
Alt Symbol | HCC-2, HMRP-2B, LKN-1, LKN1, MIP-1 delta, MIP-1D, MIP-5, MRP-2B, NCC-3, NCC3, SCYA15, SCYL3, SY15 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 15 |
Other Description | C-C motif chemokine 15|chemokine CC-2|leukotactin 1|macrophage inflammatory protein 5|new CC chemokine 3|small inducible cytokine subfamily A (Cys-Cys), member 15|small-inducible cytokine A15 |
Swissprots | Q16663 Q9UM74 B2RU34 E1P651 |
Accessions | AAC63328 EAW80110 EAW80111 EAW80112 EAW80113 Q16663 AF031587 AAB94617 AI244164 BX098368 BX497188 U58914 AAD10847 NM_004167 NM_032964 NM_032965 NP_116741 |
Function | Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. {ECO:0000269|PubMed:15905581}. |
Subcellular Location | Secreted. |
Tissue Specificity | Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients. {ECO:0000269|PubMed:15905581, ECO:0000269|PubMed:9558365}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CCL23 (H-2) - sc-393897 from Santa Cruz Biotechnology
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CCL23 (N-16) - sc-46069 from Santa Cruz Biotechnology
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MIP-5 (A-12) - sc-398069 from Santa Cruz Biotechnology
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MIP-5 (C-20) - sc-8582 from Santa Cruz Biotechnology
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MIP-5 (C-16) - sc-34982 from Santa Cruz Biotechnology
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Anti-Macrophage inflammatory protein 5 antibody - ab77004 from Abcam
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Anti-Macrophage inflammatory protein 5 antibody - ab110606 from Abcam
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Anti-Macrophage inflammatory protein 5 antibody - ab123324 from Abcam
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Anti-Macrophage inflammatory protein 5 antibody - ab14531 from Abcam
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Anti-Macrophage inflammatory protein 5 antibody - ab14532 from Abcam
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Anti-Macrophage inflammatory protein 5 antibody (Biotin) - ab83433 from Abcam
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Anti-CCL15 / MIP5 Antibody (aa18-31) - LS-C130600 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa34-49) - LS-C130601 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa78-92) - LS-C130602 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, APC) - LS-C213100 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, AP) - LS-C213099 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, Biotin) - LS-C213101 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, FITC) - LS-C213102 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, Azide-free, HRP) - LS-C213103 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody - LS-C309752 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100, PE) - LS-C213105 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa22-113, FITC) - LS-C304778 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa22-113, Biotin) - LS-C299222 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody (aa70-100) - LS-C329326 from LifeSpan Bioscience
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Anti-CCL15 / MIP5 Antibody - LS-C309753 from LifeSpan Bioscience
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