Gene Symbol | CCL15 |
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Entrez Gene | 6359 |
Alt Symbol | HCC-2, HMRP-2B, LKN-1, LKN1, MIP-1 delta, MIP-1D, MIP-5, MRP-2B, NCC-3, NCC3, SCYA15, SCYL3, SY15 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 15 |
Other Description | C-C motif chemokine 15|chemokine CC-2|leukotactin 1|macrophage inflammatory protein 5|new CC chemokine 3|small inducible cytokine subfamily A (Cys-Cys), member 15|small-inducible cytokine A15 |
Swissprots | Q16663 Q9UM74 B2RU34 E1P651 |
Accessions | AAC63328 EAW80110 EAW80111 EAW80112 EAW80113 Q16663 AF031587 AAB94617 AI244164 BX098368 BX497188 U58914 AAD10847 NM_004167 NM_032964 NM_032965 NP_116741 |
Function | Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. {ECO:0000269|PubMed:15905581}. |
Subcellular Location | Secreted. |
Tissue Specificity | Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients. {ECO:0000269|PubMed:15905581, ECO:0000269|PubMed:9558365}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
Active human Macrophage inflammatory protein 5 full length protein - ab192142 from Abcam
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Human Macrophage inflammatory protein 5 full length protein - ab105617 from Abcam
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Human Macrophage inflammatory protein 5 full length protein - ab175153 from Abcam
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Human Macrophage inflammatory protein 5 full length protein - ab176054 from Abcam
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Human Macrophage inflammatory protein 5 protein fragment - ab50223 from Abcam
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CCL15 / MIP5 Antibody Blocking Peptide - LS-E3078 from LifeSpan Bioscience
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Recombinant Human CCL15/MIP-1 delta Protein - NBP2-35065 from Novus Biologicals
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Recombinant Human CCL15/MIP-1 delta Protein - NBP2-35043 from Novus Biologicals
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CCL15/MIP-1 delta Recombinant Protein - H00006359-P01 from Novus Biologicals
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CCL15/MIP-1 delta Partial Recombinant Protein - H00006359-Q01 from Novus Biologicals
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CCL15/MIP-1 delta Recombinant Protein - P3619 from Novus Biologicals
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Recombinant Human CCL15/MIP-1 delta Protein - NBP1-99337 from Novus Biologicals
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Recombinant Human CCL15/MIP-1 delta Protein - NBP1-51080 from Novus Biologicals
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CCL15-Antibody-C-term-Blocking-Peptide - BP14217b from Abgent, a WuXi AppTec company
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MIP5 Recombinant Protein (Active) - GTX48370-PRO from GeneTex
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MIP5 recombinant protein - GTX65244 from GeneTex
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Recombinant Human CCL15/MIP-1 delta/LKN-1 (92 aa) - 363-MG-025 from R&D Systems
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Recombinant Human CCL15/MIP-1 delta/LKN-1 (92 aa), CF - 363-MG-025/CF from R&D Systems
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Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa) - 628-LK-025 from R&D Systems
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Recombinant Human CCL15/MIP-1 delta/LKN-1 (68 aa), CF - 628-LK-025/CF from R&D Systems
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MIP 5 Protein (OPPA01494) - OPPA01494 from Aviva Systems Biology
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Human MIP-5 protein - orb223903 from Biorbyt
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Human MIP5 protein - orb80155 from Biorbyt
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Human MIP 5 protein - orb168835 from Biorbyt
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Human CCL15 His tag protein - orb84381 from Biorbyt
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