CASP9

Gene Symbol	CASP9
Entrez Gene	842
Alt Symbol	APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Species	Human
Gene Type	protein-coding
Description	caspase 9, apoptosis-related cysteine peptidase
Other Description	ICE-like apoptotic protease 6|apoptotic protease MCH-6|apoptotic protease activating factor 3|caspase-9|protein phosphatase 1, regulatory subunit 56
Swissprots	Q53Y70 P55211 Q9UEQ3 O95348 Q9BQ62 Q5JRU9 Q92852 B4E1A3 Q5UGI1 Q9UIJ8
Accessions	AAO21133 BAA82697 EAW51730 EAW51731 P55211 AA534393 AB015653 BAA78780 AB020979 BAA87905 AB209147 BAD92384 AF093130 AAD12248 AF110376 AAD13615 AJ781267 CAH03131 AK292080 BAF84769 AK292111 BAF84800 AK303743 BAG64715 AY732490 AAV33129 BC002452 AAH02452 BC006463 AAH06463 BT006911 AAP35557 DA078665 DQ891693 ABM82619 HQ447255 ADQ31742 HY027003 U56390 AAC50640 U60521 AAC50776 XM_005246014 XP_005246071 XM_011542270 XP_011540572 XM_011542271 XP_011540573 XM_011542272 XP_011540574 XM_011542273 XP_011540575 XR_946778 NM_001229 NP_001220 NM_001278054 NP_001264983 NM_032996 NP_127463 NR_102732 NR_102733
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).
Tissue Specificity	Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. {ECO:0000269|PubMed:16857965}.
Top Pathways	Influenza A, p53 signaling pathway, VEGF signaling pathway, PI3K-Akt signaling pathway, Small cell lung cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Caspase-9 Human ELISA Kit - ab119508 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity 0.4 ng/ml Range 1.6 ng/ml - 100 ng/ml

Human CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F4140 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.126 ng/ml Range 0.313 - 20 ng/ml

Rat CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F4141 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313 - 20 ng/ml

Mouse CASP9 / Caspase 9 ELISA Kit (Sandwich ELISA) - LS-F4356 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156 - 10 ng/ml

Mouse/Human/Rat Phospho-CASP9 / Caspase 9 (Thr125) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1077 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human Phospho-CASP9 / Caspase 9 (Ser196) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1327 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human Phospho-CASP9 / Caspase 9 (Ser144) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1326 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human Phospho-CASP9 / Caspase 9 (Tyr153) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1325 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat CASP9 / Caspase 9 ELISA Kit (Cell-Based ELISA) - LS-F1857 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Caspase-9 Fluorometric Assay Kit - KA0765 from Novus Biologicals Category Assay Kit Prices $659.00 Sizes 1 kit

Caspase-9 Fluorometric Assay Kit - KA0764 from Novus Biologicals Category Assay Kit Prices $659.00 Sizes 1 kit

Caspase-9 Fluorometric Assay Kit - KA0763 from Novus Biologicals Category Assay Kit Prices $659.00 Sizes 1 kit

Caspase-9 Fluorometric Assay Kit - KA0762 from Novus Biologicals Category Assay Kit Prices $599.00 Sizes 1 kit

Caspase-9 Colorimetric Assay Kit - KA0761 from Novus Biologicals Category Assay Kit Prices $599.00 Sizes 1 kit

Caspase-9 Colorimetric Assay Kit - BF10100 from R&D Systems Category Assay Kit Prices $379.00 Sizes 100 tests

Caspase-9 Fluorometric Assay Kit - BF7100 from R&D Systems Category Assay Kit Prices $379.00 Sizes 100 tests

Human Caspase 9 ELISA kit - 55R-IB49680 from Fitzgerald Category ELISA Kit Prices $825.00 Sizes 96 wells

Caspase 9, CASP 9, Human, ELISA Kit - E-EL-H0663 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Caspase 9 (CASP9), Human, ELISA Kit - SEA627Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.121ng/mL Range 0.312-20ng/mL

Caspase-9, Casp-9, Human, ELISA Kit - CSB-E08862h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.195 ng/ml Range 0.78 ng/ml-50 ng/ml

Caspase-9, CASP9, Human, ELISA Kit - E0627h from ARP American Research Products Category ELISA Kit Prices $576.00 Sizes 96 t Range 0.312-20 ng/mL

Caspase-9, Human, ELISA Kit - E01C0096 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 5.0-100ng/ml

Cysteinyl Aspartate Specific Proteinases-9, Caspase-9/MCH6/ICE-LAP6, Human, ELISA Kit - YHB0926Hu from ARP American Research Products Category ELISA Kit

Caspase 9, CASP9, Mouse, ELISA Kit - E-EL-M0241 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Caspase 9, CASP9, Rat, ELISA Kit - E-EL-R0163 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

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