CASP9

Gene Symbol	CASP9
Entrez Gene	842
Alt Symbol	APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Species	Human
Gene Type	protein-coding
Description	caspase 9, apoptosis-related cysteine peptidase
Other Description	ICE-like apoptotic protease 6|apoptotic protease MCH-6|apoptotic protease activating factor 3|caspase-9|protein phosphatase 1, regulatory subunit 56
Swissprots	Q53Y70 P55211 Q9UEQ3 O95348 Q9BQ62 Q5JRU9 Q92852 B4E1A3 Q5UGI1 Q9UIJ8
Accessions	AAO21133 BAA82697 EAW51730 EAW51731 P55211 AA534393 AB015653 BAA78780 AB020979 BAA87905 AB209147 BAD92384 AF093130 AAD12248 AF110376 AAD13615 AJ781267 CAH03131 AK292080 BAF84769 AK292111 BAF84800 AK303743 BAG64715 AY732490 AAV33129 BC002452 AAH02452 BC006463 AAH06463 BT006911 AAP35557 DA078665 DQ891693 ABM82619 HQ447255 ADQ31742 HY027003 U56390 AAC50640 U60521 AAC50776 XM_005246014 XP_005246071 XM_011542270 XP_011540572 XM_011542271 XP_011540573 XM_011542272 XP_011540574 XM_011542273 XP_011540575 XR_946778 NM_001229 NP_001220 NM_001278054 NP_001264983 NM_032996 NP_127463 NR_102732 NR_102733
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).
Tissue Specificity	Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. {ECO:0000269|PubMed:16857965}.
Top Pathways	Influenza A, p53 signaling pathway, VEGF signaling pathway, PI3K-Akt signaling pathway, Small cell lung cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Caspase-9 full length protein - ab52203 from Abcam Category Protein Prices $342.00 Sizes 25 units Source E. coli Species Human

Active human Caspase-9 full length protein - ab198061 from Abcam Category Protein Prices $359.00 Sizes 50 µg Source E. coli Species Human

Caspase-9 peptide - ab171520 from Abcam Category Peptide Prices $176.00 Sizes 200 µg

Human Caspase-9 peptide - ab7885 from Abcam Category Peptide Prices $176.00 Sizes 50 µg Species Human

Human Caspase-9 peptide - ab7886 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human Caspase-9 peptide - ab100814 from Abcam Category Peptide Prices $176.00 Sizes 100 µg Species Human

Mouse Caspase-9 peptide - ab38268 from Abcam Category Peptide Species Mouse

CASP9 / Caspase 9 Antibody Blocking Peptide - LS-E7251 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CASP9 / Caspase 9 Antibody Blocking Peptide - LS-E29878 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP9 / Caspase 9 Antibody Blocking Peptide - LS-E29879 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP9 / Caspase 9 Antibody Blocking Peptide - LS-E9402 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Caspase-9 Protein - H00000842-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Caspase-9 Recombinant Protein - P4040 from Novus Biologicals Category Protein Prices $549.00 Sizes 25 units Species Human

Caspase-9 Blocking Peptide - NBP1-76961PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Caspase-9 Peptide - NBP1-76470PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Caspase-9 Protein - NBP1-99223 from Novus Biologicals Category Protein Species Human

Recombinant Human Caspase-9 Protein - NBP1-99606 from Novus Biologicals Category Protein Prices $335.00 Sizes 100 tests Source E. coli. Species Human

Caspase-9 Peptide - P1284 from Novus Biologicals Category Peptide Species Human

Recombinant Human Caspase-9 Protein - NBP1-99624 from Novus Biologicals Category Protein Prices $365.00 Sizes 50 µg Source E. coli. Species Human

Phospho-Caspase-9S196-Antibody-Blocking-peptide - BP3044a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

CASP9-Antibody-Center-Blocking-Peptide - BP7974c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Caspase 9 (proform) recombinant protein - GTX65493 from GeneTex Category Protein Prices $429.00 Sizes 50 μg Source E. coli Species Human

Caspase 9 recombinant protein - GTX65043 from GeneTex Category Protein Prices $429.00 Sizes 100 unit Source E. coli Species Human

Caspase 9 recombinant protein - GTX65044 from GeneTex Category Protein Prices $249.00 Sizes 25 unit Source E. coli Species Human

Caspase 9 peptide - GTX27885 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

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