ABCE1

Gene Symbol	ABCE1
Entrez Gene	6059
Alt Symbol	ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family E (OABP), member 1
Other Description	2'-5'-oligoadenylate-binding protein|ATP-binding cassette sub-family E member 1|RNase L inhibitor|huHP68|ribonuclease 4 inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
Swissprots	Q6NR76 P61221
Accessions	AAZ38723 EAX05049 P61221 AB062293 BAB93476 AK123593 AK315198 BC016283 AAH16283 BC016988 AAH16988 BT009779 AAP88781 DA218189 X74987 CAA52920 X76388 CAA53972 NM_001040876 NP_001035809 NM_002940 NP_002931
Function	Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. {ECO:0000269|PubMed:11585831, ECO:0000269|PubMed:9660177, ECO:0000269|PubMed:9847332}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11585831}. Mitochondrion {ECO:0000269|PubMed:11585831}. Note=Localized to clusters of virus formation at the plasma membrane.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ABCE1 full length protein - ab131962 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ABCE1 peptide - ab32269 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human ABCE1 protein fragment - ab152659 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ABCE1 Antibody Blocking Peptide - LS-E16052 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABCE1 Antibody Blocking Peptide - LS-E25929 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABCE1 Antibody Blocking Peptide - LS-E26794 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ABCE1 Protein - H00006059-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ABCE1 Protein - H00006059-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ABCE1-Antibody-C-term-Blocking-Peptide - BP16149b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABCE1 blocking peptide - GTX88692-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

ABCE1 blocking peptide - GTX88553-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

ABCE1 Blocking Peptide - 33R-4770 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ABCE1 Peptide - AC21-0758-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ABCE1 Peptide - AC21-1627-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ABCE1 - H00006059-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ABCE1 - H00006059-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ABCE1 - H00006059-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ABCE1 - H00006059-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ABCE1 Peptide - 45-183P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

RNase L Peptide - 46-735P from ProSci Category Peptide

ABCE1 fusion protein - ag0454 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ABCE1 fusion protein - ag14446 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ABCE1 fusion protein - ag1545 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ABCE1 fusion protein - Ag10659 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human ABCE1, His-tagged - ABCE1-3740H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

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