ABCE1

Gene Symbol ABCE1
Entrez Gene 6059
Alt Symbol ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family E (OABP), member 1
Other Description 2'-5'-oligoadenylate-binding protein|ATP-binding cassette sub-family E member 1|RNase L inhibitor|huHP68|ribonuclease 4 inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
Swissprots Q6NR76 P61221
Accessions AAZ38723 EAX05049 P61221 AB062293 BAB93476 AK123593 AK315198 BC016283 AAH16283 BC016988 AAH16988 BT009779 AAP88781 DA218189 X74987 CAA52920 X76388 CAA53972 NM_001040876 NP_001035809 NM_002940 NP_002931
Function Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. {ECO:0000269|PubMed:11585831, ECO:0000269|PubMed:9660177, ECO:0000269|PubMed:9847332}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11585831}. Mitochondrion {ECO:0000269|PubMed:11585831}. Note=Localized to clusters of virus formation at the plasma membrane.

ABCE1 CRISPR/Cas9 KO Plasmid (h) - sc-407729 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 HDR Plasmid (h) - sc-407729-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 Double Nickase Plasmid (h) - sc-407729-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 Double Nickase Plasmid (h2) - sc-407729-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 CRISPR Activation Plasmid (h) - sc-407729-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 CRISPR Activation Plasmid (h2) - sc-407729-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 Lentiviral Activation Particles (h) - sc-407729-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 Lentiviral Activation Particles (h2) - sc-407729-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCE1 siRNA (h) - sc-60117 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCE1 shRNA Plasmid (h) - sc-60117-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCE1 shRNA (h) Lentiviral Particles - sc-60117-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCE1 RNAi - H00006059-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU112211 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2644 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2644 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ABCE1 siRNA (Human) - CRH4099 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCE1 - MBS8205744 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ABCE1(NM_001040876.1) - SHG024841 from Creative biogene

Category siRNA
Species Reactivities Human

Human ABCE1 siRNA - orb264601 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCE1 shRNA Plasmid (Human) - CHH4099 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCE1 miRNA 3'UTR clone - MiUTR1H-00047 from Creative biogene

Species Reactivities Human

ABCE1 miRNA 3'UTR clone - MiUTR3H-03960 from Creative biogene

Species Reactivities Human
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