TULP3

Gene Symbol	TULP3
Entrez Gene	7289
Alt Symbol	TUBL3
Species	Human
Gene Type	protein-coding
Description	tubby like protein 3
Other Description	tubby-like protein 3|tubby-related protein 3
Swissprots	F8WBZ9 B7Z6A2 O75386 Q8N5B0 D3DUQ4 B3KNB7
Accessions	EAW88876 EAW88877 EAW88878 O75386 AF045583 AAC95431 AK024246 BAG51279 AK293285 BAH11483 AK307434 BC019618 BC032587 AAH32587 BP392987 EU446713 ABZ92242 JF432804 ADZ16021 NM_001160408 NP_001153880 NM_003324 NP_003315
Function	Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein- coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. {ECO:0000269|PubMed:11375483, ECO:0000269|PubMed:20889716}.
Subcellular Location	Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm {ECO:0000250}. Secreted {ECO:0000250}. Note=Does not have a cleavable signal peptide and is secreted by a non- conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide- binding protein G(q) subunit alpha. {ECO:0000250}.
Tissue Specificity	Expressed at high levels in testis, ovaries, thyroid, and spinal chord. {ECO:0000269|PubMed:9828123}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TULP3 full length protein - ab159763 from Abcam Category Protein Source Wheat germ Species Human

TULP3 Antibody Blocking Peptide - LS-E6327 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TULP3 Antibody Blocking Peptide - LS-E11825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TULP3 Antibody Blocking Peptide - LS-E13757 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TULP3 Protein - H00007289-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TULP3-Antibody-C-term-Blocking-Peptide - BP19016b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TULP3 - H00007289-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TULP3 - H00007289-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TULP3 fusion protein - ag4570 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Tubby-related protein 3(TULP3) - CSB-YP025348HU CSB-EP025348HU CSB-BP025348HU CSB-MP025348HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TULP3 - TP307595 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human TULP3 protein, MYC/DDK-tagged - TULP3-213H from Creative Biomart Category Protein Source HEK293 Species Human

TULP3 Recombinant Protein Antigen - NBP1-86897PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TULP3 Peptide, Human - M34GP16874H from Creative Peptides Category Peptide Source Synthetic. Species Human

TULP3 Recombinant Protein Antigen - NBP2-55375PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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