TULP3

Gene Symbol TULP3
Entrez Gene 7289
Alt Symbol TUBL3
Species Human
Gene Type protein-coding
Description tubby like protein 3
Other Description tubby-like protein 3|tubby-related protein 3
Swissprots F8WBZ9 B7Z6A2 O75386 Q8N5B0 D3DUQ4 B3KNB7
Accessions EAW88876 EAW88877 EAW88878 O75386 AF045583 AAC95431 AK024246 BAG51279 AK293285 BAH11483 AK307434 BC019618 BC032587 AAH32587 BP392987 EU446713 ABZ92242 JF432804 ADZ16021 NM_001160408 NP_001153880 NM_003324 NP_003315
Function Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein- coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. {ECO:0000269|PubMed:11375483, ECO:0000269|PubMed:20889716}.
Subcellular Location Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm {ECO:0000250}. Secreted {ECO:0000250}. Note=Does not have a cleavable signal peptide and is secreted by a non- conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide- binding protein G(q) subunit alpha. {ECO:0000250}.
Tissue Specificity Expressed at high levels in testis, ovaries, thyroid, and spinal chord. {ECO:0000269|PubMed:9828123}.

TULP3 CRISPR/Cas9 KO Plasmid (h) - sc-411047 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 HDR Plasmid (h) - sc-411047-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 Double Nickase Plasmid (h) - sc-411047-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 Double Nickase Plasmid (h2) - sc-411047-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 CRISPR Activation Plasmid (h) - sc-411047-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 CRISPR Activation Plasmid (h2) - sc-411047-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 Lentiviral Activation Particles (h) - sc-411047-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 Lentiviral Activation Particles (h2) - sc-411047-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TULP3 siRNA (h) - sc-77355 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULP3 shRNA Plasmid (h) - sc-77355-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TULP3 shRNA (h) Lentiviral Particles - sc-77355-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU123331 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22284 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22284 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TULP3 siRNA (Human) - CRH4983 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TULP3 - MBS8212148 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TULP3 (NM_003324.4) - SHH437952 from Creative biogene

Category siRNA
Species Reactivities Human

TULP3 shRNA Plasmid (Human) - CHH4983 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TULP3 miRNA 3'UTR clone - MiUTR3H-07048 from Creative biogene

Species Reactivities Human

TULP3 miRNA 3'UTR clone - MiUTR3H-07049 from Creative biogene

Species Reactivities Human
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