MBD3

Gene Symbol	MBD3
Entrez Gene	53615
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	methyl-CpG binding domain protein 3
Other Description	methyl-CpG-binding domain protein 3
Swissprots	Q86XF4 Q6PJZ9 D6W5Z2 O95983 A8K4B7 Q6PIL9
Accessions	AAC72104 EAW69477 EAW69478 EAW69479 EAW69480 EAW69481 O95983 AA576859 AF072247 AAC68876 AK001474 BAG50920 AK021532 AK092508 AK290882 BAF83571 AL390153 BC000872 BC009372 AAH09372 BC009438 AAH09438 BC018784 AAH18784 BC032443 AAH32443 BC043619 AAH43619 BM684485 BU181763 X58233 CAA41191 NM_001281453 NP_001268382 NM_001281454 NP_001268383 NM_003926
Function	Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. {ECO:0000269|PubMed:10947852, ECO:0000269|PubMed:12124384, ECO:0000269|PubMed:18644863, ECO:0000269|PubMed:23361464, ECO:0000269|PubMed:24307175, ECO:0000269|PubMed:9774669}.
Subcellular Location	Nucleus. Chromosome. Note=Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MBD3 full length protein - ab134609 from Abcam Category Protein Source E. coli Species Human

Human MBD3 full length protein - ab185594 from Abcam Category Protein Source E. coli Species Human

Human MBD3 peptide - ab16210 from Abcam Category Peptide

MBD3-Antibody-C-term-Blocking-Peptide - BP1038c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MBD3-Antibody-N-term-Blocking-peptide - BP13755a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MBD3 (1-291, His-tag) - AR50571PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

MBD3 (1-291, His-tag) - AR50571PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

MBD3 - H00053615-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MBD3 - H00053615-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MBD3 - H00053615-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MBD3 - H00053615-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MBD3 fusion protein - Ag5531 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MBD3 fusion protein - ag5772 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MBD3 Human - PRPS-1250 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source E.coli. Species Human

Recombinant Human MBD3, His-tagged - MBD3-28525TH from Creative Biomart Category Protein Source E. coli

MBD3 (H250) Peptide - BS2250P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Methyl-CpG-binding domain protein 3(MBD3) - CSB-YP013532HU CSB-EP013532HU CSB-BP013532HU CSB-MP013532HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MBD3 Antibody - SH-A13503 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

MBD3-Antibody-C-term-C215-Blocking-Peptide - BP1038b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MBD3-Antibody-Blocking-Peptide - BP1038a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MBD3 - PAT-81748-1 from Nordic BioSite Category Protein Species Human

MBD3 - PAT-81748-2 from Nordic BioSite Category Protein Species Human

MBD3, Recombinant Protein - MBS204158 from MyBioSource Category Protein Prices $375.00, $925.00 Sizes 50 µg, 250 µg Source E Coli Species Human

Methyl-CpG Binding Domain Protein 3, Recombinant Protein - MBS146371 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

Methyl-CpG-binding domain protein 3 (MBD3), Recombinant Protein - MBS1145918 from MyBioSource Category Protein Prices $1,045.00, $1,045.00, $1,275.00, $1,275.00, $1,625.00, $1,625.00, $2,090.00, $2,090.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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