MBD3

Gene Symbol MBD3
Entrez Gene 53615
Alt Symbol -
Species Human
Gene Type protein-coding
Description methyl-CpG binding domain protein 3
Other Description methyl-CpG-binding domain protein 3
Swissprots Q86XF4 Q6PJZ9 D6W5Z2 O95983 A8K4B7 Q6PIL9
Accessions AAC72104 EAW69477 EAW69478 EAW69479 EAW69480 EAW69481 O95983 AA576859 AF072247 AAC68876 AK001474 BAG50920 AK021532 AK092508 AK290882 BAF83571 AL390153 BC000872 BC009372 AAH09372 BC009438 AAH09438 BC018784 AAH18784 BC032443 AAH32443 BC043619 AAH43619 BM684485 BU181763 X58233 CAA41191 NM_001281453 NP_001268382 NM_001281454 NP_001268383 NM_003926
Function Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. {ECO:0000269|PubMed:10947852, ECO:0000269|PubMed:12124384, ECO:0000269|PubMed:18644863, ECO:0000269|PubMed:23361464, ECO:0000269|PubMed:24307175, ECO:0000269|PubMed:9774669}.
Subcellular Location Nucleus. Chromosome. Note=Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes.

MBD3 CRISPR/Cas9 KO Plasmid (h) - sc-401072 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 HDR Plasmid (h) - sc-401072-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 Double Nickase Plasmid (h) - sc-401072-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 Double Nickase Plasmid (h2) - sc-401072-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 CRISPR Activation Plasmid (h) - sc-401072-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 CRISPR Activation Plasmid (h2) - sc-401072-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 Lentiviral Activation Particles (h) - sc-401072-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 Lentiviral Activation Particles (h2) - sc-401072-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 siRNA (h) - sc-35867 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBD3 shRNA Plasmid (h) - sc-35867-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBD3 shRNA (h) Lentiviral Particles - sc-35867-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13072 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13072 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12723 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12723

MBD3 siRNA (Human) - CRH9974 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MBD3 CRISPR/Cas9 KO Plasmid (h2) - sc-401072-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBD3 HDR Plasmid (h2) - sc-401072-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human MBD3(NM_003926.5) - SHH179309 from Creative biogene

Category siRNA
Species Reactivities Human

MBD3 shRNA Plasmid (Human) - CHH9974 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MBD3 miRNA 3'UTR clone - MiUTR1H-06131 from Creative biogene

Species Reactivities Human
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