| Gene Symbol |
CCBL2
|
| Entrez Gene |
56267
|
| Alt Symbol |
KAT3, KATIII
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cysteine conjugate-beta lyase 2
|
| Other Description |
RP11-82K18.3|cysteine-S-conjugate beta-lyase 2|kynurenine aminotransferase III|kynurenine--glyoxylate transaminase|kynurenine--oxoglutarate transaminase 3|kynurenine--oxoglutarate transaminase III|kynurenine-oxoglutarate transaminase 3
|
| Swissprots |
Q5T9T7 Q6YP21 B3KQ13 O95335 Q5JS27 Q5T9T8 Q6ICW1 Q9BVY5 Q6AI27
|
| Accessions |
EAW73154 EAW73157 EAW73158 Q6YP21 AF091090 AAC72959 AI478599 AK057176 BAG51875 AK301326 BAG62875 AK315917 BAH14288 AL833593 AY028624 AAK26163 BC000819 AAH00819 BM728982 CR450282 CAG29278 CR627392 CAH10487 DC424120 NM_001008661 NP_001008661 NM_001008662 NP_001008662
|
| Function |
Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By similarity). {ECO:0000250}.
|
| Top Pathways |
Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism
|
![Western Blot: CCBL2 Overexpression Lysate (Adult Normal) [NBP2-11000] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCBL2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/25837_CCBL2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-11000-img0001.jpg)