| Gene Symbol | CCBL2 |
|---|---|
| Entrez Gene | 56267 |
| Alt Symbol | KAT3, KATIII |
| Species | Human |
| Gene Type | protein-coding |
| Description | cysteine conjugate-beta lyase 2 |
| Other Description | RP11-82K18.3|cysteine-S-conjugate beta-lyase 2|kynurenine aminotransferase III|kynurenine--glyoxylate transaminase|kynurenine--oxoglutarate transaminase 3|kynurenine--oxoglutarate transaminase III|kynurenine-oxoglutarate transaminase 3 |
| Swissprots | Q5T9T7 Q6YP21 B3KQ13 O95335 Q5JS27 Q5T9T8 Q6ICW1 Q9BVY5 Q6AI27 |
| Accessions | EAW73154 EAW73157 EAW73158 Q6YP21 AF091090 AAC72959 AI478599 AK057176 BAG51875 AK301326 BAG62875 AK315917 BAH14288 AL833593 AY028624 AAK26163 BC000819 AAH00819 BM728982 CR450282 CAG29278 CR627392 CAH10487 DC424120 NM_001008661 NP_001008661 NM_001008662 NP_001008662 |
| Function | Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By similarity). {ECO:0000250}. |
| Top Pathways | Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism |