Gene Symbol | CCBL2 |
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Entrez Gene | 56267 |
Alt Symbol | KAT3, KATIII |
Species | Human |
Gene Type | protein-coding |
Description | cysteine conjugate-beta lyase 2 |
Other Description | RP11-82K18.3|cysteine-S-conjugate beta-lyase 2|kynurenine aminotransferase III|kynurenine--glyoxylate transaminase|kynurenine--oxoglutarate transaminase 3|kynurenine--oxoglutarate transaminase III|kynurenine-oxoglutarate transaminase 3 |
Swissprots | Q5T9T7 Q6YP21 B3KQ13 O95335 Q5JS27 Q5T9T8 Q6ICW1 Q9BVY5 Q6AI27 |
Accessions | EAW73154 EAW73157 EAW73158 Q6YP21 AF091090 AAC72959 AI478599 AK057176 BAG51875 AK301326 BAG62875 AK315917 BAH14288 AL833593 AY028624 AAK26163 BC000819 AAH00819 BM728982 CR450282 CAG29278 CR627392 CAH10487 DC424120 NM_001008661 NP_001008661 NM_001008662 NP_001008662 |
Function | Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By similarity). {ECO:0000250}. |
Top Pathways | Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism |
KAT III (A-7) - sc-365219 from Santa Cruz Biotechnology
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KAT III (F-13) - sc-54022 from Santa Cruz Biotechnology
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KAT III (H-64) - sc-67379 from Santa Cruz Biotechnology
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KAT III (M-65) - sc-67378 from Santa Cruz Biotechnology
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KAT III (N-16) - sc-54023 from Santa Cruz Biotechnology
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Anti-CCBL2 Antibody (N-Terminus) - LS-C31785 from LifeSpan Bioscience
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Anti-CCBL2 Antibody (C-Terminus) - LS-C80308 from LifeSpan Bioscience
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CCBL2 Antibody - NBP1-87387 from Novus Biologicals
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CCBL2 Antibody - NBP1-57482 from Novus Biologicals
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CCBL2 Antibody - NBP1-87388 from Novus Biologicals
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CCBL2 Antibody - NBP1-70487 from Novus Biologicals
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Anti-CCBL2 antibody produced in rabbit - HPA026538 from Sigma-Aldrich
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Anti-CCBL2 antibody produced in rabbit - HPA027168 from Sigma-Aldrich
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Anti-CCBL2 antibody produced in rabbit - SAB2100348 from Sigma-Aldrich
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Anti-RP11-82K18.3 antibody produced in rabbit - AV40267 from Sigma-Aldrich
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CCBL2 antibody - C-terminal region (ARP40266_P050) - ARP40266_P050 from Aviva Systems Biology
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RP11-82K18.3 antibody - N-terminal region (ARP40267_T100) - ARP40267_T100 from Aviva Systems Biology
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RP11-82K18.3 antibody - 70R-1302 from Fitzgerald
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CCBL2 antibody - 70R-4897 from Fitzgerald
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Kynurenine--oxoglutaRate transaminase 3 Antibody - abx109316 from Abbexa
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Kynurenine--oxoglutaRate transaminase 3 Antibody (Biotin) - abx105615 from Abbexa
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Kynurenine--oxoglutaRate transaminase 3 Antibody (FITC) - abx107033 from Abbexa
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Kynurenine--oxoglutaRate transaminase 3 Antibody (HRP) - abx108454 from Abbexa
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RP11-82K18.3 Antibody - 29-237 from ProSci
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Kynurenic acid, Conjugated, Polyclonal Antibody - MBS616547 from MyBioSource
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