SLC6A4

Gene Symbol	SLC6A4
Entrez Gene	6532
Alt Symbol	5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Species	Human
Gene Type	protein-coding
Description	solute carrier family 6 (neurotransmitter transporter), member 4
Other Description	5-hydroxytryptamine (serotonin) transporter|5HT transporter|Na+/Cl- dependent serotonin transporter|serotonin transporter 1|sodium-dependent serotonin transporter|solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Swissprots	Q5EE02 P31645
Accessions	AAB26687 AAB93475 AAF61945 ABV02581 ACE96158 ACE96163 ACE96168 ACE96173 ACE96178 ACE96183 ACE96188 ACE96193 ACE96198 ACE96203 ACE96208 ACE96213 ACE96218 CAI53631 EAW51223 P31645 AA700070 AK308014 AK309538 AK313166 BAG35984 AU138385 AY902473 AAW80933 BC069484 AAH69484 BE645279 BQ017027 BX399758 DC345903 L05568 AAA35492 X70697 CAA50029 NM_001045 NP_001036
Function	Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner. {ECO:0000269|PubMed:17506858, ECO:0000269|PubMed:18227069, ECO:0000269|PubMed:19270731}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin.
Tissue Specificity	Expressed in platelets (at protein level). {ECO:0000269|PubMed:17506858}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Serotonin transporter full length protein - ab132415 from Abcam Category Protein Source Wheat germ Species Human

Human Serotonin transporter protein fragment - ab159522 from Abcam Category Protein Source Wheat germ Species Human

Serotonin transporter peptide - ab107104 from Abcam Category Peptide

Serotonin transporter peptide (74-84) - ab45727 from Abcam Category Peptide Species Human

SLC6A4 / SERT Antibody Blocking Peptide - LS-E27828 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC6A4 / SERT Antibody Blocking Peptide - LS-E25871 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SLC6A4/5-HTTLPR/Serotonin transporter Protein - H00006532-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SLC6A4/5-HTTLPR/Serotonin transporter Protein - H00006532-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLC6A4-Antibody-Center-Blocking-Peptide - BP17361c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Serotonin Transporter blocking peptide - GTX31103-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SLC6A4 peptide - orb73211 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

Serotonin Transporter Peptide - AC21-0701-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Serotonin Transporter Peptide - AC21-2638-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SLC6A4 / SERT - H00006532-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLC6A4 / SERT - H00006532-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SLC6A4 / SERT - H00006532-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SLC6A4 / SERT - H00006532-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SLC6A4 / SERT Control Peptide - 24332 from Acris Antibodies Category Peptide Prices $135.00 Sizes 25 µg

SLC6A4 Peptide - 46-377P from ProSci Category Peptide Species Human

SLC6A4 Peptide - 42-965P from ProSci Category Peptide Species Mouse

SLC6A4 fusion protein - ag0817 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SLC6A4, GST-tagged - SLC6A4-2783H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SLC6A4 - SLC6A4-363H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Serotonin Transporter (SERT) - RPC890Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Serotonin Transporter (SERT) - RPC890Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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