TIMM8A

Gene Symbol	TIMM8A
Entrez Gene	1678
Alt Symbol	DDP, DDP1, DFN1, MTS, TIM8
Species	Human
Gene Type	protein-coding
Description	translocase of inner mitochondrial membrane 8 homolog A (yeast)
Other Description	X-linked deafness dystonia protein|deafness dystonia protein 1|deafness/dystonia peptide|mitochondrial import inner membrane translocase subunit Tim8 A
Swissprots	Q6IRW6 B2R5A6 O60220
Accessions	EAX02853 EAX02854 O60220 AK312117 BAG35053 AW204693 BC005236 BC006994 AAH06994 BC015093 AAH15093 BC070284 AAH70284 BM467820 BQ013177 CN410182 U66035 AAC15946 NM_001145951 NP_001139423 NM_004085 NP_004076 NM_032696
Function	Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development. {ECO:0000269|PubMed:11489896, ECO:0000269|PubMed:15254020}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000269|PubMed:11489896}; Peripheral membrane protein {ECO:0000269|PubMed:11489896}; Intermembrane side {ECO:0000269|PubMed:11489896}.
Tissue Specificity	Highly expressed in fetal and adult brain, followed by fetal lung, liver and kidney. Also expressed in heart, placenta, lung, liver, kidney, pancreas, skeletal muscle and heart.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TIMM8A full length protein - ab158276 from Abcam Category Protein Source Wheat germ Species Human

Human TIMM8A full length protein - ab174417 from Abcam Category Protein Source E. coli Species Human

Human TIMM8A protein fragment - ab158277 from Abcam Category Protein Source Wheat germ Species Human

TIMM8A Partial Recombinant Protein - H00001678-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TIMM8A Recombinant Protein - H00001678-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human TIMM8A Protein - NBP2-22882 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

TIMM8A-Antibody-C-term-Blocking-Peptide - BP8545b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Ovine Leptin, MTS tag protein - orb80493 from Biorbyt Category Protein Prices $230.00, $442.00, $1,590.00 Sizes 20 μg, 100 μg, 1 mg Source E.coli Species Sheep

TIMM8A protein (His tag) - 80R-3619 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

TIMM8A (1-97, His-tag) - AR51306PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

TIMM8A (1-97, His-tag) - AR51306PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

TIMM8A - H00001678-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

TIMM8A - H00001678-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TIMM8A - H00001678-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TIMM8A, 1-97aa, Human, His tag, E.coli - 01-P2486 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

TIMM8A fusion protein - Ag1661 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant human TIMM8A, His-tagged - TIMM8A-2486H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TIMM8A, GST-tagged - TIMM8A-3239H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Mitochondrial import inner membrane translocase subunit Tim8 A(TIMM8A) - CSB-YP023557HU CSB-EP023557HU CSB-BP023557HU CSB-MP023557HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TIMM8A, 1-97aa, Human, His tag, E.coli - ATGP2486 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

TIMM8A (transcript variant 1) - TP304771 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TIMM8A Recombinant Protein Antigen - NBP1-84288PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human TIMM8A protein - orb260142 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

TIMM8A Peptide, Human - M34GP15965H from Creative Peptides Category Peptide Source Synthetic. Species Human

TIMM8A - PAT-82485-1 from Nordic BioSite Category Protein Species Human

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