Gene Symbol | BLVRB |
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Entrez Gene | 645 |
Alt Symbol | BVRB, FLR, HEL-S-10, SDR43U1 |
Species | Human |
Gene Type | protein-coding |
Description | biliverdin reductase B |
Other Description | BVR-B|FR|GHBP|NADPH-dependent diaphorase|NADPH-flavin reductase|biliverdin reductase B (flavin reductase (NADPH))|biliverdin-IX beta-reductase|epididymis secretory protein Li 10|flavin reductase (NADPH)|green heme-binding protein|short chain dehydrogenase/reductase family 43U, member 1 |
Swissprots | P30043 Q32LZ2 P32078 A6NKD8 P53005 B2R5C6 |
Accessions | AAP88933 EAW56969 EAW56970 EAW56971 EAW56972 P30043 AK312137 BAG35073 BC109371 AAI09372 BG340491 BU528444 D26308 BAA05370 D32143 BAA06874 EU794593 ACJ13647 NM_000713 NP_000704 |
Function | Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin. {ECO:0000269|PubMed:10620517}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:7929092}. |
Tissue Specificity | Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum. {ECO:0000269|PubMed:7929092}. |
Top Pathways | Riboflavin metabolism, Porphyrin and chlorophyll metabolism |
BLVRB (B-9) - sc-373692 from Santa Cruz Biotechnology
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BLVRB (FL-206) - sc-135067 from Santa Cruz Biotechnology
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BLVRB (V-16) - sc-54577 from Santa Cruz Biotechnology
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BLVRB (G-18) - sc-54575 from Santa Cruz Biotechnology
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BLVRB (P-15) - sc-54576 from Santa Cruz Biotechnology
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BLVRB (1) - sc-101519 from Santa Cruz Biotechnology
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Anti-BLVRB antibody - ab156206 from Abcam
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Anti-BLVRB antibody - ab54892 from Abcam
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Anti-BLVRB antibody [1] - ab65629 from Abcam
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Anti-BLVRB antibody - C-terminal - ab155153 from Abcam
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Anti-BLVRB antibody - C-terminal - ab188113 from Abcam
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Anti-GHBP / BLVRB Antibody (aa2-206) - LS-C182767 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, AP) - LS-C212943 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, APC) - LS-C212944 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, Biotin) - LS-C212945 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody - LS-C137592 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, Azide-free, HRP) - LS-C212947 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, FITC) - LS-C212946 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (clone 2C10) - LS-C179796 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146, PE) - LS-C212948 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (C-Terminus) - LS-C111809 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody - LS-C311024 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146) - LS-C319851 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa119-146) - LS-C157583 from LifeSpan Bioscience
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Anti-GHBP / BLVRB Antibody (aa190-201) - LS-C305851 from LifeSpan Bioscience
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