SUN1

Gene Symbol SUN1
Entrez Gene 23353
Alt Symbol UNC84A
Species Human
Gene Type protein-coding
Description Sad1 and UNC84 domain containing 1
Other Description SUN domain-containing protein 1|Sad1 unc-84 domain protein 1|protein unc-84 homolog A|sad1/unc-84 protein-like 1|unc-84 homolog A
Swissprots E9PF23 E9PDU4 O94901 B7WNY4 B7WP53 B3KMV7 Q9UH98 F8WD13 Q9HA14 A5PL20 Q96CZ7 B4DZF7
Accessions EAL23707 EAW87174 EAW87175 EAW87176 EAW87177 EAW87178 O94901 AB018353 BAA34530 AF202724 AAF15888 AK022469 BAB14046 AK022816 BAG51119 AK025737 AK074320 AK093851 AK128170 AK302896 BAG64069 AK304150 BAG65040 AK309120 AY776160 AAV52793 BC013613 AAH13613 BC113916 BC142707 AAI42708 BC151827 BC152418 AAI52419 BM689998 BX538211 CAD98070 BX640866 BX648893 BX649069 DA112466 DA666453 DA738650 NM_001130965 NP_001124437 NM_001171944 NP_001165415 NM_001171945 NP_001165416 NM_001171946 NP_001165417 NM_025154 NP_079430
Function Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). {ECO:0000250}.
Subcellular Location Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}.

SUN1 (N-19) - sc-54447 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SUN1 (N-19): sc-54447. Western blot analysis of SUN1 expression in SK-N-MC nuclear extract.

SUN1 (M-300) - sc-135075 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SUN1 (M-300): sc-135075. Western blot analysis of SUN1 expression in SK-N-MC (A), Jurkat (B) and Ramos (C) nuclear extracts.

SUN1 (H-300) - sc-135076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SUN1 (H-300): sc-135076. Western blot analysis of SUN1 expression in mouse brain tissue extract.

SUN1 (D-17) - sc-54445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SUN1 (D-17): sc-54445. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.

Anti-SUN1 antibody - ab67999 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SUN1 antibody (ab67999) at 1/500 dilutionLane 1 : SUN1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SUN1 antibody [EPR6554] - ab124770 from Abcam

Prices $397.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6554
Performed under reducing conditions.

Anti-SUN1 Antibody (Biotin) - LS-C347844 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SUN1 Antibody - LS-C348222 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SUN1 Antibody - LS-C155183 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: U87-MG B: SK-N-SH 12% SDS PAGE SUN1 antibody diluted at 1:1000

Anti-SUN1 Antibody (aa1-50) - LS-C290112 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse SUN1 by Western Blot. Samples : Whole cell lysate from HeLa (15 and 50 ug), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibody : Affinity purified rabbit anti-SUN1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-SUN1 Antibody - LS-C346256 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot blot of extracts of HeLa cell line, using SUN1 antibody.

Anti-SUN1 Antibody (Internal, clone EPR6554) - LS-C138813 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6554
IHC of paraffin-embedded human ovary carcinoma tissue using anti-SUN1 antibody.

SUN1 Antibody - NBP1-87396 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SUN1 Antibody [NBP1-87396] - Staining of human cell line A-431 shows positivity in nuclear membrane.

SUN1 Antibody - NBP1-87395 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUN1 Antibody - NBP2-20533 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: SUN1 Antibody [NBP2-20533] - A. 30 ug MCF-7 whole cell lysate/extract. B. 30 ug MDA-MB-231 whole cell lysate/extract.

SUN1 Antibody - H00023353-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SUN1 Antibody [H00023353-B01P] - Analysis of UNC84A expression in transfected 293T cell line by UNC84A polyclonal antibody. Lane 1: UNC84A transfected lysate(28.38 KDa). Lane 2: Non-transfected lysate.

SUN1 Antibody - H00023353-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SUN1 Antibody [H00023353-B02] - analysis of UNC84A expression in transfected 293T cell line by UNC84A MaxPab polyclonal antibody. Lane 1: UNC84A transfected lysate (28.27 KDa). Lane 2: Non-transfected lysate.

SUN1 Antibody (2D10) - H00023353-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D10

Monoclonal Anti-UNC84A antibody produced in mouse - SAB1403132 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D10
<B>Immunoblotting</B><BR/>Monoclonal Anti-UNC84A: <B>Cat. No. SAB1403132</B>: Antibody concentration: 1 μg/mL. Specific band of ~54.4 kDa using immunogen protein lysate.

ANTI-SUN1 antibody produced in rabbit - HPA008461 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UNC84A: <B>Cat. No. HPA008461</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human vulva/anal skin tissue showing nuclear membranous positivity in squamous epithelial cells.

ANTI-SUN1 antibody produced in rabbit - HPA008346 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UNC84A: <B>Cat. No. HPA008346</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skin tissue showing nuclear membranous positivity in epidermal and adnexal cells.

Anti-UNC84A antibody produced in mouse - SAB1407203 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-UNC84A: <B>Cat. No. SAB1407203</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-UNC84A antibody produced in rabbit - AV49929 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV49929</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type Jurkat

UNC84A antibody - N-terminal region (ARP49929_P050) - ARP49929_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC84A antibody - 70R-6253 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Search more