SUN1

Gene Symbol	SUN1
Entrez Gene	23353
Alt Symbol	UNC84A
Species	Human
Gene Type	protein-coding
Description	Sad1 and UNC84 domain containing 1
Other Description	SUN domain-containing protein 1|Sad1 unc-84 domain protein 1|protein unc-84 homolog A|sad1/unc-84 protein-like 1|unc-84 homolog A
Swissprots	E9PF23 E9PDU4 O94901 B7WNY4 B7WP53 B3KMV7 Q9UH98 F8WD13 Q9HA14 A5PL20 Q96CZ7 B4DZF7
Accessions	EAL23707 EAW87174 EAW87175 EAW87176 EAW87177 EAW87178 O94901 AB018353 BAA34530 AF202724 AAF15888 AK022469 BAB14046 AK022816 BAG51119 AK025737 AK074320 AK093851 AK128170 AK302896 BAG64069 AK304150 BAG65040 AK309120 AY776160 AAV52793 BC013613 AAH13613 BC113916 BC142707 AAI42708 BC151827 BC152418 AAI52419 BM689998 BX538211 CAD98070 BX640866 BX648893 BX649069 DA112466 DA666453 DA738650 NM_001130965 NP_001124437 NM_001171944 NP_001165415 NM_001171945 NP_001165416 NM_001171946 NP_001165417 NM_025154 NP_079430
Function	Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SUN1 full length protein - ab153219 from Abcam Category Protein Source Wheat germ Species Human

Human SUN1 full length protein - ab153220 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human SUN1 Protein - H00023353-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SUN1 Protein - H00023353-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

UNC84A Blocking Peptide - 33R-7492 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UNC84A - H00023353-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

UNC84A - H00023353-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

UNC84A - H00023353-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

UNC84A - H00023353-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

UNC84A fusion protein - ag13558 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

UNC84A fusion protein - ag21117 from Proteintech Group Category Protein Source E. coli-derived, PET30a Species Human

UNC84A fusion protein - ag13601 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SUN1 Recombinant Protein Antigen - NBP1-87396PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SUN1 Protein - NBP1-87395PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SUN1 Peptide, Human - M34GP15408H from Creative Peptides Category Peptide Source Synthetic. Species Human

SUN domain-containing protein 1 (SUN1), Recombinant Protein - MBS1168996 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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