| Gene Symbol | SUN1 |
|---|---|
| Entrez Gene | 23353 |
| Alt Symbol | UNC84A |
| Species | Human |
| Gene Type | protein-coding |
| Description | Sad1 and UNC84 domain containing 1 |
| Other Description | SUN domain-containing protein 1|Sad1 unc-84 domain protein 1|protein unc-84 homolog A|sad1/unc-84 protein-like 1|unc-84 homolog A |
| Swissprots | E9PF23 E9PDU4 O94901 B7WNY4 B7WP53 B3KMV7 Q9UH98 F8WD13 Q9HA14 A5PL20 Q96CZ7 B4DZF7 |
| Accessions | EAL23707 EAW87174 EAW87175 EAW87176 EAW87177 EAW87178 O94901 AB018353 BAA34530 AF202724 AAF15888 AK022469 BAB14046 AK022816 BAG51119 AK025737 AK074320 AK093851 AK128170 AK302896 BAG64069 AK304150 BAG65040 AK309120 AY776160 AAV52793 BC013613 AAH13613 BC113916 BC142707 AAI42708 BC151827 BC152418 AAI52419 BM689998 BX538211 CAD98070 BX640866 BX648893 BX649069 DA112466 DA666453 DA738650 NM_001130965 NP_001124437 NM_001171944 NP_001165415 NM_001171945 NP_001165416 NM_001171946 NP_001165417 NM_025154 NP_079430 |
| Function | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}. |
Human SUN1 cDNA clone(NM_001171944.1) - CDFH018984 from Creative Biomart
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Human SUN1 cDNA clone(NM_001171945.1) - CDFH018985 from Creative Biomart
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Human SUN1 cDNA clone(NM_001171946.1) - CDFH018986 from Creative Biomart
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Human SUN1 ORF clone(NM_025154.5) - CDCH402888 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171944.1) - CDCR356372 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171944.1) - CDCR356374 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171945.1) - CDCR356375 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171946.1) - CDCR356376 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171946.1) - CDCR356377 from Creative Biomart
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Human SUN1 ORF Clone(NM_001171945.1) - CDCR356380 from Creative Biomart
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human SUN1 ORF clone - CDCH087588 from Creative Biomart
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human SUN1 ORF clone - CDCH087589 from Creative Biomart
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human SUN1 ORF clone - CDCH087590 from Creative Biomart
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human SUN1 ORF clone - CDCH087591 from Creative Biomart
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human SUN1 ORF clone - CDCH087592 from Creative Biomart
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human SUN1 ORF clone - CDCH087593 from Creative Biomart
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human SUN1 ORF clone - CDCH087594 from Creative Biomart
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human SUN1 ORF clone - CDCH087595 from Creative Biomart
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human SUN1 ORF clone - CDCH087596 from Creative Biomart
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human SUN1 ORF clone - CDCH087597 from Creative Biomart
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Human UNC84A Gene ORF cDNA clone in cloning vector - HG13472-G from Sino Biological
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Human UNC84A Gene ORF cDNA clone expression plasmid, N-His tag - HG13472-NH from Sino Biological
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Human UNC84A Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13472-ACG from Sino Biological
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Human UNC84A Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13472-ANG from Sino Biological
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Human UNC84A Gene ORF cDNA clone expression plasmid, C-His tag - HG13472-CH from Sino Biological
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