SUN1

Gene Symbol SUN1
Entrez Gene 23353
Alt Symbol UNC84A
Species Human
Gene Type protein-coding
Description Sad1 and UNC84 domain containing 1
Other Description SUN domain-containing protein 1|Sad1 unc-84 domain protein 1|protein unc-84 homolog A|sad1/unc-84 protein-like 1|unc-84 homolog A
Swissprots E9PF23 E9PDU4 O94901 B7WNY4 B7WP53 B3KMV7 Q9UH98 F8WD13 Q9HA14 A5PL20 Q96CZ7 B4DZF7
Accessions EAL23707 EAW87174 EAW87175 EAW87176 EAW87177 EAW87178 O94901 AB018353 BAA34530 AF202724 AAF15888 AK022469 BAB14046 AK022816 BAG51119 AK025737 AK074320 AK093851 AK128170 AK302896 BAG64069 AK304150 BAG65040 AK309120 AY776160 AAV52793 BC013613 AAH13613 BC113916 BC142707 AAI42708 BC151827 BC152418 AAI52419 BM689998 BX538211 CAD98070 BX640866 BX648893 BX649069 DA112466 DA666453 DA738650 NM_001130965 NP_001124437 NM_001171944 NP_001165415 NM_001171945 NP_001165416 NM_001171946 NP_001165417 NM_025154 NP_079430
Function Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non- coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity). Required for efficient localization of SYNE4 in the nuclear envelope (By similarity). {ECO:0000250}.
Subcellular Location Nucleus inner membrane {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}; Single-pass type II membrane protein {ECO:0000269|PubMed:12958361, ECO:0000269|PubMed:16445915, ECO:0000269|PubMed:17132086, ECO:0000269|PubMed:18845190, ECO:0000269|PubMed:19933576}.

SUN1 CRISPR/Cas9 KO Plasmid (h) - sc-403236 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 HDR Plasmid (h) - sc-403236-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 Double Nickase Plasmid (h) - sc-403236-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 Double Nickase Plasmid (h2) - sc-403236-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 CRISPR Activation Plasmid (h) - sc-403236-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 CRISPR Activation Plasmid (h2) - sc-403236-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 Lentiviral Activation Particles (h) - sc-403236-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 Lentiviral Activation Particles (h2) - sc-403236-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUN1 siRNA (h) - sc-106672 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUN1 shRNA Plasmid (h) - sc-106672-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUN1 shRNA (h) Lentiviral Particles - sc-106672-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUN1 RNAi - H00023353-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU124871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20837 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20837 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SUN1 siRNA (Human) - CRH8203 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SUN1 - MBS8237319 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SUN1 (NM_025154.5) - SHH420944 from Creative biogene

Category siRNA
Species Reactivities Human

SUN1 shRNA Plasmid (Human) - CHH8203 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SUN1 miRNA 3'UTR clone - MiUTR3H-09419 from Creative biogene

Species Reactivities Human

SUN1 miRNA 3'UTR clone - MiUTR3H-09420 from Creative biogene

Species Reactivities Human
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