FGD1

Gene Symbol	FGD1
Entrez Gene	2245
Alt Symbol	AAS, FGDY, MRXS16, ZFYVE3
Species	Human
Gene Type	protein-coding
Description	FYVE, RhoGEF and PH domain containing 1
Other Description	FYVE, RhoGEF and PH domain-containing protein 1|faciogenital dysplasia 1 protein|rho/Rac GEF|rho/Rac guanine nucleotide exchange factor FGD1|zinc finger FYVE domain-containing protein 3
Swissprots	Q8N4D9 Q5H999 P98174
Accessions	EAW93179 EAW93180 EAW93181 P98174 AK226117 AK299635 BAG61561 BC034530 AAH34530 U11690 AAA57004 NM_004463 NP_004454
Function	Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. {ECO:0000269|PubMed:8969170}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with membrane ruffles and lamellipodia. {ECO:0000250}.
Tissue Specificity	Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
Top Pathways	Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FGD1 peptide - ab45555 from Abcam Category Peptide Species Human

FGD1 Antibody Blocking Peptide - LS-E13826 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FGD1 Blocking Peptide - 33R-3737 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FGD1 Blocking Peptide - 33R-9977 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FGD1 fusion protein - ag3861 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human FGD1, GST-tagged - FGD1-12857H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human FYVE, RhoGEF and PH domain-containing protein 1(FGD1) ,partial - CSB-YP008609HU CSB-EP008609HU CSB-BP008609HU CSB-MP008609HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FGD1 - TP305133 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FGD1 Recombinant Protein Antigen - NBP1-83906PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FGD1 Peptide, Human - M34GP05688H from Creative Peptides Category Peptide Source Synthetic. Species Human

FYVE, RhoGEF and PH domain-containing protein 1 (FGD1), partial, Recombinant Protein - MBS966177 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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