FGD1

Gene Symbol FGD1
Entrez Gene 2245
Alt Symbol AAS, FGDY, MRXS16, ZFYVE3
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 1
Other Description FYVE, RhoGEF and PH domain-containing protein 1|faciogenital dysplasia 1 protein|rho/Rac GEF|rho/Rac guanine nucleotide exchange factor FGD1|zinc finger FYVE domain-containing protein 3
Swissprots Q8N4D9 Q5H999 P98174
Accessions EAW93179 EAW93180 EAW93181 P98174 AK226117 AK299635 BAG61561 BC034530 AAH34530 U11690 AAA57004 NM_004463 NP_004454
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. {ECO:0000269|PubMed:8969170}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with membrane ruffles and lamellipodia. {ECO:0000250}.
Tissue Specificity Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
Top Pathways Regulation of actin cytoskeleton

FGD1 CRISPR/Cas9 KO Plasmid (h) - sc-407706 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 HDR Plasmid (h) - sc-407706-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 Double Nickase Plasmid (h) - sc-407706-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 Double Nickase Plasmid (h2) - sc-407706-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 CRISPR Activation Plasmid (h) - sc-407706-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 CRISPR Activation Plasmid (h2) - sc-407706-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 Lentiviral Activation Particles (h) - sc-407706-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 Lentiviral Activation Particles (h2) - sc-407706-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD1 siRNA (h) - sc-41711 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD1 shRNA Plasmid (h) - sc-41711-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD1 shRNA (h) Lentiviral Particles - sc-41711-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD1 RNAi - H00002245-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8639 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8639 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06322 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06322

FGD1 siRNA (Human) - CRH1565 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGD1 - MBS8207858 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Fgd1 (NM_004463.2) - SHH294289 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FGD1(NM_004463.2) - SHH056459 from Creative biogene

Category siRNA
Species Reactivities Human

FGD1 shRNA Plasmid (Human) - CHH1565 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FGD1 miRNA 3'UTR clone - MiUTR1H-03620 from Creative biogene

Species Reactivities Human
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