FGD1

Gene Symbol FGD1
Entrez Gene 2245
Alt Symbol AAS, FGDY, MRXS16, ZFYVE3
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 1
Other Description FYVE, RhoGEF and PH domain-containing protein 1|faciogenital dysplasia 1 protein|rho/Rac GEF|rho/Rac guanine nucleotide exchange factor FGD1|zinc finger FYVE domain-containing protein 3
Swissprots Q8N4D9 Q5H999 P98174
Accessions EAW93179 EAW93180 EAW93181 P98174 AK226117 AK299635 BAG61561 BC034530 AAH34530 U11690 AAA57004 NM_004463 NP_004454
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. {ECO:0000269|PubMed:8969170}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with membrane ruffles and lamellipodia. {ECO:0000250}.
Tissue Specificity Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
Top Pathways Regulation of actin cytoskeleton

FGD1 (E-10) - sc-374389 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FGD1 (E-10): sc-374389. Western blot analysis of FGD1 expression in non-transfected: sc-117752 (A) and human FGD1 transfected: sc-113935 (B) 293T whole cell lysates.

FGD1 (C-18) - sc-8486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FGD1 (C-18): sc-8486. Western blot analysis of FGD1 expression in non-transfected: sc-117752 (A) and human FGD1 transfected: sc-113935 (B) 293T whole cell lysates.

FGD1 (G-18) - sc-11109 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FGD1 (G-18): sc-11109. Western blot analysis of FGD1 expression in non-transfected: sc-117752 (A) and human FGD1 transfected: sc-113935 (B) 293T whole cell lysates.

Anti-FGD1 antibody - ab104789 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FGD1 antibody (ab104789) at 1 µg/ml + Transfected 293T cell lysate at 10 µg

Anti-FGD1 Antibody (C-Terminus) - LS-C30041 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Raji Cell Lysate

Anti-FGD1 Antibody (N-Terminus) - LS-C80209 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

FGD1 Antibody - NBP1-79979 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FGD1 Antibody [NBP1-79979] - Raji cell lysate, concentration 0.2-1 ug/ml.

FGD1 Antibody - NBP1-83906 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FGD1 Antibody - NBP1-80304 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD1 antibody produced in rabbit - AV31673 from Sigma-Aldrich

Prices $316.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Raji (<B>Cat. No. AV31673</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.0 μg/mL in cell type Raji

Anti-FGD1 antibody produced in rabbit - SAB2100813 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FGD1: <B>Cat. No.SAB2100813</B>: FGD1 in Transfected 293T cell lysate with FGD1 antibody at 1.0 μg/mL.

FGD1 antibody - C-terminal region (ARP31673_P050) - ARP31673_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FGD1 antibody - N-terminal region (ARP38472_P050) - ARP38472_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FGD1 antibody - GTX114404 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-FGD1 antibody used in Western blot. GTX114404

FGD1 antibody - 70R-8259 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

FGD1 antibody - 70R-7877 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

FGD1 Antibody - 27-391 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Raji at 0.2-1 ug/ml.

FGD1 antibody - 13141-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

FGD1 Antibody - GWB-80483C from Genway Biotech

Prices $369.00
Sizes 50 µg
Clonality Polyclonal

FGD1 Antibody - EPP13054 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal

FGD1, Polyclonal Antibody - MBS2516489 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD1 Antibody (C-Terminus) IHC-plus™ - LS-B12576 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

FGD1-antibody-N-terminal-region-AI12071 - AI12071 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-FGD1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Transfected 293T

Anti-FGD1 antibody produced in rabbit - HPA000911 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FGD1: <B>Cat. No. HPA000911</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing positive staining of cells in ductus seminiferus.

FGD1 antibody - TA343464 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-FGD1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T
Search more