Gene Symbol | FARP2 |
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Entrez Gene | 9855 |
Alt Symbol | FIR, FRG, PLEKHC3 |
Species | Human |
Gene Type | protein-coding |
Description | FERM, RhoGEF and pleckstrin domain protein 2 |
Other Description | FERM domain including RhoGEF|FERM, RhoGEF and pleckstrin domain-containing protein 2|FGD1-related Cdc42-GEF|PH domain-containing family C member 3|pleckstrin homology domain-containing family C member 3 |
Swissprots | F5GZ84 B7Z6J8 Q53QM5 Q8WU27 O94887 Q9UFE7 |
Accessions | AAY14682 EAW71262 EAW71263 O94887 AB018336 BAA34513 AK127510 AK300435 BAH13284 AL122052 CAB59185 AW014580 BC021301 AAH21301 BC036887 BQ028038 DB451463 HY312568 JF432117 ADZ15334 XM_005247050 XP_005247107 XM_011512233 XP_011510535 XM_011512234 XP_011510536 XM_011512235 XP_011510537 XM_011512236 XP_011510538 XM_011512237 XP_011510539 NM_001282983 NP_001269912 NM_001282984 NP_001269913 NM_014808 NP_055623 |
Function | Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). {ECO:0000250}. |
Top Pathways | Adherens junction, Rap1 signaling pathway |
FARP2 (D-14) - sc-167842 from Santa Cruz Biotechnology
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FARP2 (H-199) - sc-135121 from Santa Cruz Biotechnology
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FARP2 (S-14) - sc-167844 from Santa Cruz Biotechnology
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FIR (B-5) - sc-398785 from Santa Cruz Biotechnology
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FIR (E-6) - sc-398799 from Santa Cruz Biotechnology
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Anti-FARP2 antibody - ab64984 from Abcam
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Anti-FARP2 antibody - ab194462 from Abcam
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Anti-FARP2 antibody - ab177098 from Abcam
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Anti-FARP2 antibody - ab172567 from Abcam
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Anti-FARP2 / FRG Antibody (aa277-293) - LS-C3267 from LifeSpan Bioscience
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Anti-FARP2 / FRG Antibody (Pro364) - LS-C191925 from LifeSpan Bioscience
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Anti-FARP2 / FRG Antibody - LS-C310320 from LifeSpan Bioscience
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Anti-FARP2 / FRG Antibody (aa331-380) - LS-C118724 from LifeSpan Bioscience
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FARP2 Antibody - NBP1-84680 from Novus Biologicals
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FARP2 Antibody - H00009855-A01 from Novus Biologicals
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FARP2 Antibody - H00009855-D01P from Novus Biologicals
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FARP2 Polyclonal Antibody - bs-11459R from Bioss
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FARP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11459R-A350 from Bioss
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FARP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11459R-A488 from Bioss
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FARP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11459R-A555 from Bioss
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FARP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11459R-A647 from Bioss
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FARP2 Polyclonal Antibody, Cy3 Conjugated - bs-11459R-Cy3 from Bioss
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FARP2 Polyclonal Antibody, Cy5 Conjugated - bs-11459R-Cy5 from Bioss
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FARP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11459R-Cy5.5 from Bioss
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FARP2 Polyclonal Antibody, Cy7 Conjugated - bs-11459R-Cy7 from Bioss
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