Gene Symbol | FARP2 |
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Entrez Gene | 9855 |
Alt Symbol | FIR, FRG, PLEKHC3 |
Species | Human |
Gene Type | protein-coding |
Description | FERM, RhoGEF and pleckstrin domain protein 2 |
Other Description | FERM domain including RhoGEF|FERM, RhoGEF and pleckstrin domain-containing protein 2|FGD1-related Cdc42-GEF|PH domain-containing family C member 3|pleckstrin homology domain-containing family C member 3 |
Swissprots | F5GZ84 B7Z6J8 Q53QM5 Q8WU27 O94887 Q9UFE7 |
Accessions | AAY14682 EAW71262 EAW71263 O94887 AB018336 BAA34513 AK127510 AK300435 BAH13284 AL122052 CAB59185 AW014580 BC021301 AAH21301 BC036887 BQ028038 DB451463 HY312568 JF432117 ADZ15334 XM_005247050 XP_005247107 XM_011512233 XP_011510535 XM_011512234 XP_011510536 XM_011512235 XP_011510537 XM_011512236 XP_011510538 XM_011512237 XP_011510539 NM_001282983 NP_001269912 NM_001282984 NP_001269913 NM_014808 NP_055623 |
Function | Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). {ECO:0000250}. |
Top Pathways | Adherens junction, Rap1 signaling pathway |
Human FARP2 full length protein - ab160683 from Abcam
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Human FARP2 protein fragment - ab160684 from Abcam
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Recombinant Human FARP2 Protein - H00009855-Q01 from Novus Biologicals
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Recombinant Human FARP2 Protein - H00009855-P01 from Novus Biologicals
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PUF60 blocking peptide - GTX89681-PEP from GeneTex
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FARP2 - H00009855-P01-10 from Acris Antibodies
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FARP2 - H00009855-P01-25 from Acris Antibodies
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FARP2 - H00009855-Q01-10 from Acris Antibodies
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FARP2 - H00009855-Q01-25 from Acris Antibodies
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FARP2 fusion protein - ag15929 from Proteintech Group
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FARP2 fusion protein - Ag1990 from Proteintech Group
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FIR (P364) Peptide - BS1895P from Bioworld Technology
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Recombinant Human FERM, RhoGEF and pleckstrin domain-containing protein 2(FARP2) - CSB-YP008428HU CSB-EP008428HU CSB-BP008428HU CSB-MP008428HU from Cusabio
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FARP2 Recombinant Protein Antigen - NBP1-84680PEP from Novus Biologicals
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FARP2 Peptide, Human - M34GP05534H from Creative Peptides
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FERM, RhoGEF and pleckstrin domain-containing protein 2 (FARP2), partial, Recombinant Protein - MBS1200376 from MyBioSource
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FARP2 Recombinant Protein Antigen - NBP2-57178PEP from Novus Biologicals
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