MAGEC2

Gene Symbol MAGEC2
Entrez Gene 51438
Alt Symbol CT10, HCA587, MAGEE1
Species Human
Gene Type protein-coding
Description melanoma antigen family C2
Other Description MAGE-C2 antigen|MAGE-E1 antigen|cancer/testis antigen 10|hepatocellular cancer antigen 587|hepatocellular carcinoma-associated antigen 587|melanoma antigen family C, 2|melanoma antigen, family E, 1, cancer/testis specific|melanoma-associated antigen C2
Swissprots Q5JZ00 Q9P1M6 Q9P1M7 Q96D45 Q9UBF1
Accessions AAF07211 AAF34817 AAK15073 EAW78014 EAW78015 EAW78016 Q9UBF1 AF116194 AAF34816 AF151378 AAF36533 AF196482 AAF07210 AK313591 BAG36358 BC005891 AAH05891 BC013318 AAH13318 BM548987 BP370466 CR457168 CAG33449 DQ892942 ABM83868 DQ896191 ABM87190 NM_016249 NP_057333
Function Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12920247}. Nucleus {ECO:0000269|PubMed:12920247}. Note=Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
Tissue Specificity Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non- small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is a inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression. {ECO:0000269|PubMed:12097419, ECO:0000269|PubMed:12920247}.

melanoma antigen family C, 2, ELISA Kit - MBS9318895 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MAGEC2 ELISA Kit - E024025 from Biobool

Category ELISA Kit

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9352767 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9361531 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9343919 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Category ELISA Kit
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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9347697 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9355119 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9368710 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9351697 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9364968 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9358468 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9361332 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9369314 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9367049 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9354498 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9371524 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9352685 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9368568 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9354388 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-Associated Antigen C2 (MAGEC2), ELISA Kit - MBS9362286 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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