MAGEC2

Gene Symbol MAGEC2
Entrez Gene 51438
Alt Symbol CT10, HCA587, MAGEE1
Species Human
Gene Type protein-coding
Description melanoma antigen family C2
Other Description MAGE-C2 antigen|MAGE-E1 antigen|cancer/testis antigen 10|hepatocellular cancer antigen 587|hepatocellular carcinoma-associated antigen 587|melanoma antigen family C, 2|melanoma antigen, family E, 1, cancer/testis specific|melanoma-associated antigen C2
Swissprots Q5JZ00 Q9P1M6 Q9P1M7 Q96D45 Q9UBF1
Accessions AAF07211 AAF34817 AAK15073 EAW78014 EAW78015 EAW78016 Q9UBF1 AF116194 AAF34816 AF151378 AAF36533 AF196482 AAF07210 AK313591 BAG36358 BC005891 AAH05891 BC013318 AAH13318 BM548987 BP370466 CR457168 CAG33449 DQ892942 ABM83868 DQ896191 ABM87190 NM_016249 NP_057333
Function Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12920247}. Nucleus {ECO:0000269|PubMed:12920247}. Note=Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
Tissue Specificity Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non- small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is a inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression. {ECO:0000269|PubMed:12097419, ECO:0000269|PubMed:12920247}.

MAGE-C2 (K-15) - sc-68603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MAGE-C2 (K-15): sc-68603. Western blot analysis of MAGE-C2 expression in 293T whole cell lysate.

MAGE-C2 (N-20) - sc-68604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MAGE-C2 (V-20) - sc-68605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MAGE-C2 (V-20): sc-68605. Western blot analysis of MAGE-C2 expression in K-562 (A), Hep G2 (B), A431 (C) and MDA-MB-231 (D) whole cell lysates.

MAGE-C2/C3 (H-57) - sc-68852 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-MAGEE1 antibody - ab111361 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MAGEE1 antibody (ab111361) at 1 µg/ml + 721_B cell lysate at 10 µg

Anti-MAGEE1 antibody - ab169119 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MAGEE1 antibody (ab169119) at 1 µg/mlLane 1 : MAGEE1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-MAGEC2 / CT10 Antibody (aa88-103) - LS-C3340 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, AP) - LS-C219961 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, APC) - LS-C219960 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, FITC) - LS-C219964 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, Azide-free, HRP) - LS-C219965 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, Biotin) - LS-C219963 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus, PE) - LS-C219966 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (N-Terminus) - LS-C330522 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (aa102-151) - LS-C135651 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MAGEC2 antibody LS-C135651 Western blot of 721_B cell lysate.

Anti-MAGEC2 / CT10 Antibody - LS-C308860 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MAGEC2 / CT10 Antibody (aa237-282) - LS-C313973 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Melanoma antigen family C2 Antibody - NBP2-34145 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Melanoma antigen family C2 Antibody - NBP1-68961 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Melanoma antigen family C2 Antibody [NBP1-68961] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

Melanoma antigen family C2 Antibody - H00051438-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Melanoma antigen family C2 Antibody [H00051438-B01] - analysis of MAGEC2 expression in transfected 293T cell line by MAGEC2 MaxPab polyclonal antibody (B01). Lane 1: MAGEC2 transfected lysate (41.20 KDa). Lane 2: Non-transfected lysate.

Melanoma antigen family C2 Antibody - H00051438-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Melanoma antigen family C2 Antibody [H00051438-B01P] - Analysis of MAGEC2 expression in human placenta.

Anti-MAGEC2 antibody produced in mouse - SAB1409424 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MAGEC2: <B>Cat. No. SAB1409424</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~41 kDa using MAGEC2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-MAGEE1 (N-term) antibody produced in rabbit - SAB1300324 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MAGEE1 (N-term) Antibody: <B>Cat. No. SAB1300324</B>: MAGEE1 in human breast carcinoma tissue with Anti-MAGEE1 (N-term) Antibody at 40 μg/mL.

Anti-MAGEC2 antibody produced in rabbit - HPA062230 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MAGEC2: <B>Cat. No. HPA062230</B>: Immunohistochemical staining of Human testis shows strong nuclear positivity in cells in seminiferous ducts.

MAGEC2 antibody - N-terminal region (ARP59888_P050) - ARP59888_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more