PTGES2

Gene Symbol	PTGES2
Entrez Gene	80142
Alt Symbol	C9orf15, GBF-1, GBF1, PGES2, mPGES-2
Species	Human
Gene Type	protein-coding
Description	prostaglandin E synthase 2
Other Description	GATE-binding factor 1\|gamma-interferon-activated transcriptional element-binding factor 1\|mPGE synthase-2\|membrane-associated prostaglandin E synthase 2\|membrane-associated prostaglandin E synthase-2\|microsomal prostaglandin E synthase-2\|prostaglandin-H(2) E-isomerase
Swissprots	Q96GI0 Q5SYV6 Q9H7Z7 Q53EW9 Q96GL2
Accessions	EAW87741 EAW87742 EAW87743 EAW87744 EAW87745 EAW87746 Q9H7Z7 AK024100 BAB14826 AK057049 BAG51854 AK223520 BAD97240 AK301618 BAG63103 AL525982 AM392565 CAL37443 AW073370 BC009397 AAH09397 BC009456 AAH09456 BC011613 AAH11613 BE797008 BG481657 BG823488 BI761840 BI826720 BM739176 BQ889675 BX493085 DQ891904 ABM82830 DQ895090 ABM86016 XM_005252239 XP_005252296 XM_011519050 XP_011517352 XM_011519051 XP_011517353 NM_001256335 NP_001243264 NM_025072 NP_079348 NM_198938 NP_945176 NM_198939 NM_198940 NR_027812
Function	Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2). {ECO:0000269\|PubMed:12804604, ECO:0000269\|PubMed:18198127}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269\|PubMed:12835322}; Single-pass membrane protein {ECO:0000269\|PubMed:12835322}.
Tissue Specificity	Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer. {ECO:0000269\|PubMed:11866447}.
Top Pathways	Arachidonic acid metabolism

PGE synthase 2 (A-2) - sc-514224 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

PGE synthase 2 (A-2): sc-514224. Western blot analysis of PGE synthase 2 expression in non-transfected 293T: sc-117752 (A), human PGE synthase 2 transfected 293T: sc-172625 (B) and COLO 320DM (D) whole cell lysates and human heart tissue extract (C).

PGE synthase 2 (L-12) - sc-160662 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-PTGES2 antibody - ab172772 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-PTGES2 antibody (ab172772) at 1 µg/mlLane 1 : PTGES2 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PTGES2 antibody - ab57769 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab57769 PTGES2 antibody at 1ug/ml.

Anti-PTGES2 Antibody (clone 2C3) - LS-C174315 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2C3

IHC of paraffin-embedded Human bladder tissue using anti-PTGES2 mouse monoclonal antibody.

Anti-PTGES2 Antibody IHC-plus™ - LS-B6962 from LifeSpan Bioscience

Prices	$395.00
Sizes	1 ea
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6962 concentration 5 ug/ml.

Anti-PTGES2 Antibody - LS-C109473 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-PTGES2 Antibody (aa86-135) - LS-C152045 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (N-Terminus) - LS-C152044 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (aa144-384, Biotin) - LS-C300014 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (aa144-384, FITC) - LS-C302275 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (aa56-105) - LS-C187147 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

PTGES2 antibody Western Blot of Mouse Brain. Antibody dilution: 1 ug/ml.

Anti-PTGES2 Antibody (aa281-330) - LS-C170168 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (aa144-384) - LS-C296066 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody (aa145-357) - LS-C314653 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTGES2 Antibody - LS-C346246 from LifeSpan Bioscience

Prices	$255.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence blot of A549 cell using PTGES2 antibody. Blue: DAPI for nuclear staining.

Prostaglandin E Synthase 2/PTGES2 Antibody - AF7627 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

Western blot shows lysates of SW480 human colorectal adenocarcinoma cell line, COLO 205 human colorectal adenocarcinoma cell line, HepG2 human hepatocellular carcinoma cell line, A549 human lung carcinoma cell line, and human heart tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Prostaglandin E Synthase 2/PTGES2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7627) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Prostaglandin E Synthase 2/PTGES2 at approximately 30-32 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Prostaglandin E Synthase 2/PTGES2 Antibody - NBP1-86709 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: PTGES2 Antibody [NBP1-86709] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

Prostaglandin E Synthase 2/PTGES2 Antibody - NBP1-33411 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Prostaglandin E Synthase 2/PTGES2 Antibody - H00080142-B01 from Novus Biologicals

Prices	$359.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: Prostaglandin E Synthase 2/PTGES2 Antibody [H00080142-B01] - Analysis of PTGES2 expression in transfected 293T cell line by PTGES2 polyclonal antibody. Lane1:PTGES2 transfected lysate(41.47 KDa). Lane2:Non-transfected lysate.

Prostaglandin E Synthase 2/PTGES2 Antibody - H00080142-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: Prostaglandin E Synthase 2/PTGES2 Antibody [H00080142-D01P] - Analysis of PTGES2 expression in transfected 293T cell line by PTGES2 polyclonal antibody.Lane 1: PTGES2 transfected lysate(41.90 KDa).Lane 2: Non-transfected lysate.

Prostaglandin E Synthase 2/PTGES2 Antibody - H00080142-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: Prostaglandin E Synthase 2/PTGES2 Antibody [H00080142-B01P] - Analysis of PTGES2 expression in transfected 293T cell line by PTGES2 polyclonal antibody. Lane1:PTGES2 transfected lysate(41.47 KDa). Lane2:Non-transfected lysate.

Prostaglandin E Synthase 2/PTGES2 Antibody (5B7) - H00080142-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	5B7

Western Blot: Prostaglandin E Synthase 2/PTGES2 Antibody (5B7) [H00080142-M01] - Analysis of PTGES2 expression in transfected 293T cell line by PTGES2 monoclonal antibody (M01), clone 5B7.Lane 1: PTGES2 transfected lysate (Predicted MW: 41.9 KDa).Lane 2: Non-transfected lysate.

Prostaglandin E Synthase 2/PTGES2 Antibody - H00080142-D01 from Novus Biologicals

Prices	$399.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Prostaglandin E Synthase 2/PTGES2 Antibody - H00080142-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

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