PTGES2

Gene Symbol	PTGES2
Entrez Gene	80142
Alt Symbol	C9orf15, GBF-1, GBF1, PGES2, mPGES-2
Species	Human
Gene Type	protein-coding
Description	prostaglandin E synthase 2
Other Description	GATE-binding factor 1|gamma-interferon-activated transcriptional element-binding factor 1|mPGE synthase-2|membrane-associated prostaglandin E synthase 2|membrane-associated prostaglandin E synthase-2|microsomal prostaglandin E synthase-2|prostaglandin-H(2) E-isomerase
Swissprots	Q96GI0 Q5SYV6 Q9H7Z7 Q53EW9 Q96GL2
Accessions	EAW87741 EAW87742 EAW87743 EAW87744 EAW87745 EAW87746 Q9H7Z7 AK024100 BAB14826 AK057049 BAG51854 AK223520 BAD97240 AK301618 BAG63103 AL525982 AM392565 CAL37443 AW073370 BC009397 AAH09397 BC009456 AAH09456 BC011613 AAH11613 BE797008 BG481657 BG823488 BI761840 BI826720 BM739176 BQ889675 BX493085 DQ891904 ABM82830 DQ895090 ABM86016 XM_005252239 XP_005252296 XM_011519050 XP_011517352 XM_011519051 XP_011517353 NM_001256335 NP_001243264 NM_025072 NP_079348 NM_198938 NP_945176 NM_198939 NM_198940 NR_027812
Function	Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2). {ECO:0000269|PubMed:12804604, ECO:0000269|PubMed:18198127}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:12835322}; Single-pass membrane protein {ECO:0000269|PubMed:12835322}.
Tissue Specificity	Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer. {ECO:0000269|PubMed:11866447}.
Top Pathways	Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTGES2 full length protein - ab107954 from Abcam Category Protein Source E. coli Species Human

PTGES2 Antibody Blocking Peptide - LS-E13433 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTGES2 Antibody Blocking Peptide - LS-E13434 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTGES2 Antibody Blocking Peptide - LS-E23904 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTGES2 Antibody Blocking Peptide - LS-E23903 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Prostaglandin E Synthase 2/PTGES2 Recombinant Protein - H00080142-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Prostaglandin E Synthase 2/PTGES2 Partial Recombinant Protein - H00080142-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Prostaglandin E Synthase 2/PTGES2 Protein - NBP1-72306 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Recombinant Human PTGES2, CF - 7627-PS-020 from R&D Systems Category Protein Source E. coli-derived, Glu88-His377, with an N-terminal Met and 6-His tag

Human PTGES2 protein - orb169111 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

PTGES2 protein (His tag) - 80R-1816 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

PTGES2 (1-186, His-tag) - AR09999PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PTGES2 (1-186, His-tag) - AR09999PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PTGES2 - H00080142-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PTGES2 - H00080142-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PTGES2 - H00080142-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Prostaglandin E Synthase 2, Human Recombinant - 228-12287-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human Prostaglandin E Synthase 2 - 228-12287-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Prostaglandin E Synthase 2 - 228-12287-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

PTGES2 fusion protein - Ag1329 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PTGES2 Human - ENPS-143 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Prostaglandin E Synthase 2 Enzyme - BP002779-ENZ-136 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human Prostaglandin E Synthase 2, His-tagged - PTGES2-993H from Creative Biomart Category Protein

Recombinant Human PTGES2, His-tagged - PTGES2-30326TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PTGES2, GST-tagged - PTGES2-2045H from Creative Biomart Category Protein Source E.coli Species Human

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