VPS25

Gene Symbol	VPS25
Entrez Gene	84313
Alt Symbol	DERP9, EAP20, FAP20
Species	Human
Gene Type	protein-coding
Description	vacuolar protein sorting 25 homolog (S. cerevisiae)
Other Description	ELL-associated protein of 20 kDa|ESCRT-II complex subunit VPS25|dermal papilla-derived protein 9|vacuolar protein-sorting-associated protein 25
Swissprots	B2R581 Q9BRG1
Accessions	EAW60879 EAW60880 Q9BRG1 AB014763 BAB87804 AK312092 BAG35028 BC006282 AAH06282 BU630023 HQ448303 ADQ32783 NM_032353 NP_115729
Function	Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. {ECO:0000269|PubMed:18723511}.
Subcellular Location	Cytoplasm. Endosome membrane. Nucleus, nucleoplasm. Note=Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
Tissue Specificity	Expressed at the mRNA level in kidney, liver, pancreas, and placenta. Lower levels of expression are found in heart, skeletal muscle, brain and lung. {ECO:0000269|PubMed:16889659}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human VPS25 full length protein - ab124321 from Abcam Category Protein Source E. coli Species Human

VPS25 peptide (20-29) - ab45840 from Abcam Category Peptide Species Human

VPS25 Antibody Blocking Peptide - LS-E22152 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VPS25 Antibody Blocking Peptide - LS-E26016 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VPS25 Recombinant Protein - H00084313-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human VPS25 Protein - NBP1-99072 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

VPS25 blocking peptide - GTX89428-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human VPS25 protein - orb169549 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

VPS25 protein (His tag) - 80R-2191 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

VPS25 Peptide - AC21-0844-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

VPS25 (1-176, His-tag) - AR50272PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

VPS25 (1-176, His-tag) - AR50272PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

VPS25 - H00084313-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

VPS25 - H00084313-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

VPS25, 1-176aa, Human, His tag, E.coli - 01-P1447 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

VPS25 Peptide - 46-578P from ProSci Category Peptide Species Human

VPS25 fusion protein - Ag8243 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

VPS25 fusion protein - Ag8134 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

VPS25, 1-176aa, Recombinant Protein - GWB-P0591F from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human VPS25, His-tagged - VPS25-3672H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Vacuolar protein-sorting-associated protein 25(VPS25) - CSB-YP887108HU CSB-EP887108HU CSB-BP887108HU CSB-MP887108HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

VPS25 - TP302487 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

VPS25, 1-176aa, Human, His tag, E.coli - ATGP1447 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Vacuolar Protein Sorting 25, Recombinant Protein - MBS144839 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

Vacuolar protein-sorting-associated protein 25 (VPS25) , Recombinant Protein - MBS1332040 from MyBioSource Category Protein Prices $1,370.00, $1,370.00, $1,825.00, $1,825.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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