WTAP

Gene Symbol WTAP
Entrez Gene 9589
Alt Symbol Mum2
Species Human
Gene Type protein-coding
Description Wilms tumor 1 associated protein
Other Description PNAS-132|WT1-associated protein|Wilms' tumour 1-associating protein|female-lethal(2)D homolog|hFL(2)D|pre-mRNA-splicing regulator WTAP|putative pre-mRNA splicing regulator female-lethal(2D)|wilms tumor 1-associating protein
Swissprots Q9BYJ7 Q15007 Q5TCL9 Q9H4E2 Q96T28 Q5TCL8
Accessions EAW47622 EAW47623 EAW47624 EAW47625 EAW47626 EAW47627 EAW47628 Q15007 AA706250 AF277190 AAK07548 AF374416 AAK54764 AJ276706 CAC10188 AK127822 BAG54579 AK131393 AK290854 BAF83543 AL583911 CAC29495 BC000383 AAH00383 BC004432 AAH04432 BC028180 BC069192 AAH69192 BE906617 BG702882 BQ778248 BQ948913 BX387163 CN284477 CR627456 CAH10537 D14661 BAA03495 DA138013 DA561768 HQ447554 ADQ32040 XM_011536264 XP_011534566 NM_001270531 NP_001257460 NM_001270532 NP_001257461 NM_001270533 NP_001257462 NM_004906 NP_004897 NM_152857 NP_690596 NM_152858 NP_690597
Function Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. {ECO:0000269|PubMed:12444081, ECO:0000269|PubMed:17088532, ECO:0000269|PubMed:17095724, ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location Nucleus, nucleolus. Nucleus speckle.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11001926}.

Mouse/Human WTAP ELISA Kit (Cell-Based ELISA) - LS-F3197 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 0.156-10 pmol/ml

Pre-mRNA-splicing regulator WTAP, WTAP, Human, ELISA Kit - E1509h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.156-10 nmol/L

Pre-mRNA-splicing regulator WTAP, ELISA Kit - MBS282653 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

WTAP Colorimetric Cell-Based ELISA - CB6011 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

Mouse WTAP ELISA Kit (Custom ELISA) - LS-F17809 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 pmol/ml

Human WTAP ELISA Kit (Custom ELISA) - LS-F17810 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 pmol/ml

Human Pre-mRNA-splicing regulator WTAP ELISA Kit - abx251063 from Abbexa

Category ELISA Kit
Range 0.156 nmol/l - 10 nmol/l

WTAP ELISA Kit - DEIA-XYA1832 from Creative Diagnostics

Category ELISA Kit

Human Pre-mRNA-splicing regulator WTAP ELISA Kit - EKE53495 from Biomatik

Category ELISA Kit
Prices $685.40, $2,912.95, $5,483.20
Sizes 96 t, 5x96t, 10x96t
Sensitivity The minimum detectable dose of this kit is typically less than 0.078 nmol/L
Range 0.156-10 nmol/L

WTAP - EKH3518 from Nordic BioSite

Sensitivity 0.094pmol/ml
Range 0.156-10pmol/ml

Human WTAP ELISA Kit - E030475 from Biobool

Category ELISA Kit

WTAP ELISA Kit (Human) (OKEH04206) - OKEH04206 from Aviva Systems Biology

Category ELISA Kit
Prices $596.00
Sizes 96 wells
Sensitivity < 0.07 nmol/L
Range 0.156 - 10 nmol/L

Pre-mRNA-splicing regulator WTAP, ELISA Kit - MBS763953 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094pmol/ml
Range 0.156-10pmol/ml

Pre-mRNA-splicing regulator WTAP, ELISA Kit - MBS2883281 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.156-10 nmol/L

Human WTAP ELISA Kit (Sandwich ELISA) - LS-F33251 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.094
Range 0.156-10 pmol/ml

WTAP Colorimetric Cell-Based ELISA Kit - EKA50847 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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